Anesthesia For Non-Ob Surgery Flashcards
What population is more predisposed to anomalies
DM 4-12%
Vs 3%
When is fetus most voluntarable and why
Between 15-90 days - organogenesis
After this mostly functional defects or growth retardation
What group of meds is associated with congenital anomalies
Tranquilizers
Minor BZDP
Major Psych meds
Cleft lip/palate is associate with
Tranquilizers, salicylates, opiates
Valium: most common
No studies suggest that a single dose is ass with congenital defects
Why not to use N2O
- Teratogenic effects
- Adverse effects on DNA synthesis
- Inactivates B12:
- essential cofactor for enzyme methionine synthetase
- interferes with folate metabolism
- conversion of uridine to thymidine - Increase uterine adrenergic tone- vc to uterine blood flow
Propofol
B: Ok to use, rapidly crosses placenta
Ketamine
Not classified
Can depress Apgar score
Which med group to avoid during all trimesters
BZDP
D
Narcotics
Muscle relaxant
Narcotic safe
Droperidol and Zofran ok to use
Ketorolac
Not used, avoid after 1st trimester
May constrict or close fetal DA
Muscle relaxant don’t cross placenta
What is #1 cause of non OB maternal mortality
Homicide #1
Trauma is most common
What are the 3 H’s that decrease uterine perfusion
Hypoxia
Hypocarbia
Hypotension
When to start aspiration prophylaxis
14 weeks: bicitra, Pepcid, Reglan
Most likely need to be GETA : RSI
Narcotic and antisialagogue OK
When to start fetal heart monitoring
After 16 - 18 weeks
What does hypocarbia do
Decreased umbilical blood flow because of direct vasoconstriction
OxyHgb curve shifts to left: fetal hypoxia, metabolic acidosis