Anesthesia Flashcards
In pt with positive lip signs how successful was man 1st molar block? 1st premolar? Lat incisor?
Molar 53%
1st premolar 60%
Lat incisor 40%
How successful are IAN blocks in teeth with irreversible pulpitis
20-70%
Teeth with inflamed pulps are how many times more likely not to achieve plural anesthesia
8x
Describe Aβ
nerve fibers
The largest are the A- beta, heavily myelinated and responsible for touch and pressure, fastest
Describe Aδ
fibers
Then there are the A-delta fibers, a little smaller in diameter and with a slower conduction velocity. These fibers are responsible for pain, temperature and touch. They are also myelinated.
Describe C fibers
small, unmyelinated C-fibers responsible for the throbbing pain associated with tissue injury, slowest conduction speed
A delta pain description
Temperature sensitive
- Often sharp
Short Duration
C fiber pain description
Temperature sensitive
- Often sharp
Short Duration
Compare nerve fiber sensitivity to lido
Aβ > Aδ > C
Therefore – if your patient has a numb lip (Aβ), then the pulp is not necessarily anesthetized
Two important points about c fibers
C fibers are the hardest to anesthetize
C fibers are the most resistant to necrosis (irreversible pulpitis)
What are some anatomical mechanisms of IAN failure
Needle placement Accessory nerves Size of the nerve Length of nerve exposed Type of sodium channel
What are some inflammatory mechanisms of failure for IAN blocks
Local pH Inflammatory mediators Sprouting Central sensitization Neuropeptides Local blood flow
How many nodes of ranvier need to be blocked for nerve blockade
Initially thought to be 3 now believed to be 4
What are TTX-r sodium channels
New Sodium Channel discovered that is resistant to local anesthetic
Tetrodotoxin resistant sodium channel (TTX-r)
Takes 4 x more anesthetic to block action potential
what form of the anesthetic can diffuse through the membrae
non ionized form
What is the average pH of the extracellular space
7.4
Which form of the anesthetic blocks the channel
ionized
How does PGE2 affect ability to anesthetize
Sensitizes neurons Mense Brain Research 1981
Doubles the activity of TTX-resistant (TTX-r) sodium channels
alter structural properties of nociceptors
-nerves sprout into areas of inflammation
-greater field, spatial summation of stimuli, activation
what is central sensitization
Barrage of afferent impulses
Exaggerated response to gentle peripheral stimuli
Does anxiety play a part in anesthesia
Anxious patients reported greater pain
Prior painful treatment or anxiety about treatment led to an increase in reported pain
Different procedures caused more anxiety
Does a 2nd IAN block increase success if positive lip sign already present
no
What are some advantages of a low gates nerve block
True V3 block Inferior alveolar Buccal Lingual Mylohyoid Low positive aspiration rate (1.8%) Constancy of landmarks