Anemia Pharmacology

Question 1

Anemia

Answer 1

Decrease in RBC count, hemoglobin, and or hematocrit values resulting in a lower ability of blood to carry oxygen to tissues

Question 2

Normal iron levels and daily intake

Answer 2

3-4 g in circulating RBC

19-20 mg per day for men
17-19 mg per day for women

Question 3

Iron Deficiency Anemia

Major Causes

Answer 3

Decreased dietary intake

Reduced absorption (upper GI, duodenum max absorption) due to disease, parasite, surgery

Blood loss (overt or occult)

Question 4

Iron Deficiency Anemia

Symptoms

Answer 4

Fatigue, weakness
Headache, irritability
Exertional dyspnea, exercise intolerance
Microcytic hypochromic anemia
Pica (eat non food substances)
Pagophagia (ice craving)

Question 5

Ferrous sulfate

Answer 5

Iron deficiency supplement

Question 6

Iron dextran

Answer 6

Iron deficiency supplement

Question 7

Folic acid

Answer 7

B9 and sometimes B12 deficiency supplement

Question 8

Cyanocobalamin

Answer 8

B12 deficiency supplement

Question 9

Epoetin alfa

Answer 9

Growth factor

Increases RBC

Reduced need for transfusion

Recombinant

Question 10

Filgrastim

Answer 10

Growth factor

Increase WBC, especially neutrophils

Decrease infection risk

Recombinant

Question 11

Oprelvekin

Answer 11

IL 11 issues

Increase platelets by increasing megakaryocytes

Recombinant

Question 12

Romiplostim

Answer 12

Growth factor

Increase platelets by activist group TPO (thrombopoietin) receptor

Recombinant