Anemia, Cytopenias And Thrombosis Flashcards
3 typical signs or symptoms of acute anemia.
- Tachycardia
- Orthostatic hypotension
- Dyspnea
List 9 typical symptoms of a chronic drop in hgb.
- Fatigue
- Decreased appetite
- Decreased exercise capacity
- Dizziness
- Headache
- Syncope
- Tinnitus
- Vertigo
- Impaired cognitive function
List 7 disease related causes of anemia in palliative care.
- Bone marrow infiltration
- Blood loss
- Hemolysis
- Anemia of chronic disease
- Cancer treatments
- Folate deficiency from malnutrition
- GI resections.
List two cancer treatment related causes of anemia.
- Myelosuppression from chemotherapy.
2. Treatment related myelodysplastic syndrome.
What are the red blood cell features of normocytic anemia?
Normocytic, normochromatic
Which cancers are commonly associated with hemorrhage? (9)
- GI
- Head and neck
- Respiratory
- Uterine
- Urinary
- Bulky sarcomas
- Hepatomas
- Melanomas
- Ovarian cancers
List 3 non pharm ways to control bleeding.
- Surgically
- Endoscopically
- Radiation
What is the usual dose of parenteral iron per day for adults?
150-200mg of elemental iron a day
List 4 common side effects of po iron.
- Nausea
- Diarrhea
- Heartburn
- Constipation
List 3 indications for parenteral iron.
- Intolerant of oral iron
- Intestinal absorption issues
- Losing iron more quickly than it can be replaced orally.
List 6 common side effects of parenteral iron.
- Hypotension
- Cramps
- Nausea
- Vomiting
- Headaches
- Diarrhea
What is the recommended dietary intake of folic acid?
0.4mg per day
List 3 cancers commonly associated with bone marrow infiltration.
- Lung
- Breast
- Prostate
What are 4 common biochemical signs of bone marrow infiltration from malignancy?
- Leucoerythroblastic blood
- Presence of immature nucleated red cells
- Myeloid white cell precursors
- Teardrop shaped red cells
What CBC pattern is common in bone marrow infiltration from solid tumours? (3)
- Elevated WBC
- Low hgb
- Low, normal or elevated plts