anemia Flashcards
loss of appetite, smooth/ sore tongue, diarrhea or constipation, paresthesias, loss of coordination, tremor, irritability, somnolence, abnormal taste/smell are signs of
B12 deficiency
what are some common S/Sx of anemia
pallor, weakness, fatigue, SOB, tachycardia, palpitations, murmur
what are some common causes of B12 deficiency anemia
gastric atrophy/surgery, deficiency of intrinsic factor for ilial absorption, IBD, bacterial overgrowth,
what drugs commonly cause B12 deficiency
colchicine (for gout), neomycin (Abx), metformin, PPI
what are some common causes of folic acid deficiency
ETOH abuse, prego, celiac sprue
what drugs commonly cause altered folate metabolism
primidine, phenobarbital, methotrexate, OCP, bactrim
what are some common causes of iron deficiency anemia
menorrhagia, PUD, hiatal hernia, gastrectomy, gastritis (2/2 ETOH, ASA, NSAIDS), IBD, GI bleed, bacterial overgrowth of small bowel, pica (starch dec bioavail of ingested iron)
microcytic hypochromic anemia
iron deficiency anemia
serum ferritin stores are markedly____ in iron deficiency anemia
reduced
serum iron ____ and TIBC____ in iron deficiency anemia
decreases, increases