Andy Flashcards
What is pleiotropy?
One locus affects two or more traits
What is epistasis?
Alleles at one locus affect the expression of alleles at a different locus
What is linkage?
Two or more loci are on the same chromosome
What are the requirements of the Hardy Weinberg equilibrium to be applicable?
Large random mating population
In the absence of:
- migration
- mutation
- selection
What is migration?
The movement of alleles from one population to another
What does the proportion of alleles in the new population depend on
- immigration rate
- difference in allele frequencies between the two populations
What is selection?
The process that determines which individuals become the parents of the next generation
What is natural selection
the environment deciding which individuals are the parents of the next generation (adapt or perish)
What is artificial selection?
Humans decide which individuals are the parents of the next generation (goal oriented)
Qualitative traits vs quantitative traits
Qualitative
- controlled by one or few loci
- discrete phenotypes (eye colour, coat colour etc.)
Quantitative
- controlled by multiple loci
- continuous phenotypes (height, weight, racing speed, milk yield, temperament) - assign categories based on perceived thresholds
What are threshold traits
quantitative traits that are controlled by many genes, categorized by small number of discrete phenotypic classes
What is variance?
A measure of how much variability there is within a population for a certain trait
What are the three genetic components?
- additive (A): a measure of the sum of effects of individual alleles
- dominance (D): a measure of the combined dominance effects of individual loci
- interaction (I): a measure of the combined interactions between loci (epistasis)
What is heritability?
Proportion of total variance that is additive genetic and 1/2 is transmitted from parent to offspring (h^2) (proportion of phenotype that is passed on from generation to generation)
What are the three heritability ranges?
low 1-20% - reproduction and fitness traits
medium 20-35% - performance traits, some aspects of temperament
high 35% and up - conformation traits, growth and body composition traits