Androgens and Related Drugs

Question 0

What is injectable and long-acting replacment therapy for testosterone?

Answer 0

Testosterone esters

Question 1

What is an endogenous androgen, has new routes of admin

Answer 1

Testosterone

Question 2

Prototype of 17-alkyl analogs

Answer 2

Methyltestosterone

Question 3

What is commonly abused by athletes and body builders?

Answer 3

Anabolic steroids

Question 4

T/F: Testosterone is effective orally.

Answer 4

False: Ineffective orally; limited parenteral effectiveness due to rapid metabolism. Topical preps are effective

Question 5

What form of testosterone is for IM injection?

Answer 5

Testosterone esters

Question 6

What are the therapeutic uses of Testosterone and testosterone esters?

Answer 6

1) Replacement therapy for androgenic effects in prepubertal or postpubertal hypogonadism, hypopituitarism.
2) To induce or maintain secondary sexual characteristics and to prevent osteoporosis in male hypogonadism.
- Gonadotropins (FSH, LH) required for induction of spermatogenesis and fertility, so androgen replacement will not restore fertility.

Question 7

Drugs with supposedly higher ratio of anabolic to androgenic effectiveness, designed to provide anabolic effects with less masculinizing side effects. What are they?

Answer 7

Anabolic steroids- schedule III drugs

Question 8

What is used mainly in treating prostate and other cancers, not endocrine use

Answer 8

Anti-androgens