Anderson CNS HIstory Flashcards
1
Q
When an axon is injured, the distal portion dies, how is death regulated and what does depend on?
A
Neuron can either:
1.DIE
2.DO NOTHING
3.REGENERATE
Depends on type of neuron
2
Q
Where can axons regenerate
A
In adult mammalian peripheral nerves
axonal sprouts regenerate and regrow along pre-existing fibre hoepfuly join to target organ and continue function.
It is hard to stop them regenerating
3
Q
How many axons are there post injury?
A
More axons post injury (conditioned lesion effect)
4
Q
Axonal regeneration in species ranking
A
Axonal regeneration in fish>amphibians>reptiles>mammals
but even in mammals some functional recovery may be achieved
5
Q
What happens in a PNS axontomy
A
