Ancient Drugs Flashcards

1
Q

How do we measure the ‘success’ of a
drug?

A

 We can measure the reduction in deaths caused by
a particular disease.
 We can measure the closure of hospitals such as TB
facilities or mental hospitals.

 But these measures don’t capture all the effects of a
drug on a society
» It doesn’t tell us whether the quality of life of the
former patients improved or not

 It’s almost impossible to measure the effects of
ancient drugs on populations because of
confounding factors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

The Doctor’s Chest was called The ……………………….. Cargo.
Discovered? Excavated?

A

The Pozzino shipwreck cargo

Discovered in 1974; excavated 1989-90

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

The Medicine contained …. tablets contained 75% …….

A

5 tablets containing 75% Zinc

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

How can we explain the use of zinc from the medicine chest?

A

Pliny and Dioscorides both describe how
zinc compounds (calamine)used to treat
eyes and skin complaint

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

 The recipe only worked against MRSA when it was
followed exactly: (3)

A

 The recipe only worked against MRSA when it was
followed exactly:
>You needed the right combination of ingredients
> The right preparatory method
> The right waiting time

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

CNS stimulating plants

A

 hemp plant – leaves and buds
 opium poppy – seed-head
 coca leaves - chewed
 betel nut - chewed
 kava leaves - chewed
 tobacco – smoked or chewed
 peyote - a cactus which produces mescalin
 mushrooms - psilocybin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Mineral Sources

A

 Clay – kaolinite
 Chalk
 Red ochre – iron salts?
 Mercury
 Arsenic
 Metal containers, e.g. bronze
 Verdigris – copper carbonate –
artists’ pigment
 Gold, silver, antimony, zin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Alcohol has what medicinal properties?

A

Antiseptic and anaesthetic properties

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Medicinal Sources

A

 Raw honey
 Insects – blister beetle = cantharides; spiders; ants;
locusts
 Animal organs and tissues –ox gall (bile salts);
hair, horns, dung
 Human body parts – hair, urine, blood, fat
 Mummies –powdered for asphalt and ingested in
medicines – artist’s pigment
 Manuscripts–spells written on slips of paper and
swallowed

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Longest and most famous of the ancient Egyptian medical
papyrii.

A

 The Ebers Papyrus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Gall and wine are both anti-………..
 Raw honey is anti-………

A

Gall and wine are both astringent.
Raw honey is antiseptic.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Author of De Materia Medica, the first authoritative
Western pharmacoepia (c.50-70 CE).

A

Pedanius Dioscorides (40-90 CE):

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Pedanius Dioscorides (40-90 CE) is…

A

Author of De Materia Medica, the first authoritative
Western pharmacoepia (c.50-70 CE).

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

……….. theory underpinned Islamic approach to
drug therapy.

A

Humoral theory underpinned Islamic approach to
drug therapy.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Al Razi introduced …….. to pharmacopeia

A

Mercury

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Paracelsus was a …….ologist (2)

A

Minerologist and Toxicologist

17
Q

Cannabidiol and Chamomile shows some anti….. properties

A

Cannabidiol and Chamomile shows some anticonvulsant properties

18
Q

Aspirin’s key ingredient is ……..

A

Salicyclic Acid

19
Q

Is replicating ancient recipe worth it?

A

 they deteriorate over time and
have very limited shelf-life.
 they usually cannot be easily
mass-produced.
 they cannot be easily
transported.
 BUT: it’s fun and occasionally
successful.
 It might lead to new pathways in
research for isolating effective trace
elements