ANCA Vasculitis Part 5 Pauci-immune Glomerulonephritis

Question 1

Pauci-immune glomerulonephritis

Answer 1

c-ANCA which is PR3 - 20%

p-ANCA which is MPO - 70%

Negative ANCA in about 10%

Question 2

Pauci-immune glomerulonephritis

Answer 2

Age of onset is 5th to 7th decade of life with a slight male predominance. More common in white than black.

Question 3

Pauci-immune glomerulonephritis

Answer 3

Lungs - no lung involvement is noted

Question 4

Pauci-immune glomerulonephritis

Answer 4

In the kidneys there is ANCA positive glomerulonephritis but without classical manifestations or symptomatology for MPA, GPA, or EGPA.

Question 5

Pauci-immune glomerulonephritis

Answer 5

There is no gastrointestinal, skin, neurological or other organ involvement in this disease.