Anatomy & Regional Flashcards

1
Q

Cervical plexus derived from … and it’s branches supplies …

A

C1 to C4

Paravertebral muscle
Strap muscles of neck
Phrenic nerve

The prevertebral muscles receive branches from the cervical plexus. The cervical plexus is a plexus of the anterior rami of the first four cervical spinal nerves which arise from C1 to C4 cervical segments in the neck. It is located in the neck, deep to the sternocleidomastoid muscle, and supplies branches to the prevertebral muscles, strap muscled of the neck, and the phrenic nerve.

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2
Q

Superficial vs deep cervical block

A

Superficial cervical block; targets 5 cutaneous nerves

1) transverse cervical N
2) supraclavicular N
3) lesser occipital N
4) Greater occipital N
5) Greater auricular N

Done for procedures in the distribution of C2-C4 including LN dissection, carotid endarterectomy, or bilateral block for tracheostomy/thyroidectomy

Location: midpoint of posterior border of SCM

Complications: possible block the accessory (XI) nerve

Deep cervical block: are the paravertebral block of C2 to C4 as they emerge from foramina in cervical vertebrae

Location: at the C4 transverse process

Complications:
Intravascular injection
Blockade of phrenic and superior laryngeal nerve
Spread to epidural and subarachnoid spaces

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3
Q

3 nerves blocked for awake intubate are

A

1) sup laryngeal
- Location: through thyrohyoid membrane
- targets: inferior aspect of epiglottis to VC

2) Translaryngeal block (recurrent laryngeal N)
- through cricothyroid membrane
- anesthesia of trachea and below VC

3) glossopharyngeal N
- each post tonsillar pillar (extra-oral block), intra-oral block avoided due to proximity to carotid artery
- anesthesia to post 1/3 tongue, pharynx, sup surface of epiglottis

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4
Q

Stellate ganglion block

A

The mother of cervical sympathetic trunk contains 3 interconnected ganglia: sup, middle and inferior

In 80% ppl, the lowest cervical ganglia is fused with first thoracic ganglia to form cervicothoracic (stellate) ganglion

Anatomy considerations:
Anterior to prevertebral fascia
Medial to carotid sheath
* vertebral artery (branch of SC) passes anterior to stellate ganglion (at C7) and enters vertebral foramina (as it goes cephalad, 80% of ppl this artery will go posterior to the anterior tubercle of C6)

Block location -> medial to carotid pulse, anterior to the C6 transverse process (Chassaignac’s tubercle of C6)

The Chassaignac’s tubercle identified: 3 cm cephalad to sternoclavicular joint, at the medial border of SCM.

Test of good block by testing adrenergic fiber activity (thermography, plethysmography, lesser Doppler flowmetry) combined with testing sympathetic cholinergic activity (sweat test, sympathogalvanic response)

Increased skin temperature is commonly used (the presence of Horner’s dose not imply a sympathetic blockade of the arm).

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5
Q

Which central line placement could lead to thoracic duct injury

A

Left SC

Thoracic duct arches over the subclavian artery, descending to empty into the left IJ and SC

Injury could result into chylothorax EXUDATIVE plural effusion

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6
Q

Epidural space boundaries

A

Extends from foramina magnum to sacral hiatus

Anterior: posterior longitudinal ligament
Lateral: Pedicles + intervertebral foramina
Posterior: ligamentum falvum

Epidural needle go through
Midline: interspinous -> supraspinous -> L.flavum

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7
Q

Surface landmark and their spinous prominence

A

Cervical spinous prominence -> C7

Scapular spine -> T3 spinous process

Nipple lines -> T4

Inferior angle of scapula -> T7 spinous process

Lower ribs -> T12

Iliac crest -> L4-5

Posterior superior iliac spine -> S2 spinous process

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8
Q

Cervical plexus superficial vs deep block?

A

The cervical plexus is unique in that it divides early into cutaneous branches, penetrating the cervical fascia and deeper muscular branches that innervate the muscles and joints, which can be blocked separately.

The deep cervical plexus supplies the musculature of the neck segmentally and the cutaneous sensation of the skin between the trigeminally innervated face and the T2 dermatome of the trunk.

The superficial cervical plexus is blocked at the midpoint of the posterior border of the sternocleidomastoid muscle. The deep cervical plexus block is a paravertebral block of the C2 to C4 spinal nerves as they emerge from the foramina in the cervical vertebrae.

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9
Q

A 56-year-old patient presents to the preop clinic for evaluation. He has a history of hepatic cysts that require surgical removal. Which one of the following percentages of blood flow is supplied to the liver from the hepatic artery and portal vein?

A. 90% hepatic artery and 10% portal vein
B. 50% hepatic artery and 50% portal vein
C. 25% hepatic artery and 75% portal vein
D. 10% hepatic artery and 10% portal vein
E. 75% hepatic artery and 25% portal vein

A

The hepatic artery supplies about 25% of total hepatic blood flow, while the portal vein supplies 75% of total hepatic blood flow. Because the blood flowing through the hepatic artery has a higher oxygen content, the hepatic artery and portal vein each end up delivering approximately 50% of the total oxygen supply to the liver.

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10
Q

A healthy patient presents for ankle fusion surgery and regional anesthesia is planned. Which nerve has a characteristic anatomic bifurcation which is often used in identifying the structure with ultrasound?

A. Obturator block
B. Lateral femoral cutaneous block
C. Sciatic block, popliteal approach
D. Femoral nerve block
E. Saphenous nerve block below the knee
F. Axillary block
A

The sciatic nerve is a single structure from the subgluteal/upper portion of the leg but bifurcates into the tibial and common peroneal nerves in the popliteal fossa. This “splitting” of the nerve is a pathognomonic sign for the identification of the sciatic nerve. The femoral nerve also bifurcates into anterior and posterior branches, but this bifurcation is not consistent and is not used sonographically for the purposes of performing a regional block.

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11
Q

A 23-year-old, woman with idiopathic intracranial hypertension is scheduled to have a ventriculoperitoneal shunt placed under general anesthesia. The shunt will be placed into the anterior aspect of the patient’s right lateral ventricle. How does cerebral spinal fluid from the lateral ventricle pass into the third ventricle?

A. Through the foramen of Magendie
B. Through the foramen of Luschka
C. Through the aqueduct of Sylvius
D. Through the foramen of Monro
E. Through the cisterna magna
A

This patient has a type of communicating hydrocephalus requiring shunting in order to limit damage to the optic nerve.

Cerebral spinal fluid (CSF) is formed in the choroid plexuses located in the cerebral ventricles. CSF from the two lateral ventricles proceeds through the foramen of Monro into the third ventricle. From the third ventricle, CSF passes through the aqueduct of Sylvius into the fourth ventricle. From the fourth ventricle, CSF moves through the lateral foramen of Luschka and middle foramen of Magendie into the cisterna magna. CSF then flows through the subarachnoid spaces in a superior direction towards the arachnoid villi where it is absorbed into venous circulation.

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12
Q

Which one of the following choices listed below includes structures associated with the basal ganglia?

A. Putamen, caudate nucleus, globus pallidus, subthalamus and corpus callosum
B. Putamen, caudate nucleus, substantia gelatinosa, substantia nigra and corpus callosum
C. Hippocampus, caudate nucleus, substantia nigra, putamen and lateral geniculate body
D. Putamen, caudate nucleus, corpus callosum, lateral geniculate body and subthalamus
E. Putamen, caudate nucleus, globus pallidus, substantia nigra and subthalamus

A

The limbic system consists of the hippocampus and basal ganglia. A large portion of the basal ganglia’s signals are inhibitory in nature and this structure plays an important role in movement disorders such as Parkinson’s disease. The basal ganglia consist of 5 structures, namely the putamen, caudate nucleus, globus pallidus, substantia nigra and subthalamus. Damage to the caudate and putamen cause choreiform movements, while destruction of the substantia nigra results in the rigidity characteristic of Parkinson’s disease.
The corpus callosum consists of fibers that connect the two hemispheres of the cerebral cortex, making information stored in one hemisphere available to the other hemisphere. The substantia gelatinosa is a portion of the dorsal horn containing intermediate neurons that transmit temperature, pain, and tactile information to the spinothalamic tract. Finally, the lateral geniculate bodies are areas where the optic tracts synapse before passing to the occipital area of the cerebral cortex.

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13
Q

An elderly patient with lung cancer requires the positioning of a double lumen tube via fiberoptic bronchoscopy for thoracic surgery. In what percentage of patients is the right upper lobe orifice seen in the trachea proper, as opposed to the right mainstem bronchus?

A

The right upper lobe (RUL) opens from the trachea in 2-3% of patients. This is important because, in these instances, a right-sided double-lumen ETT will require meticulous positioning to line up its side orifice (“Murphy eye”) with the RUL orifice. In certain anatomic variants, this may not be possible based on the geometry of the ETT, and alternate methods of lung isolation will have to be considered.

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14
Q

Where the CSF located in spinal cord?

A

Subarachnoid/interthecal space (between the pia mater and the arachnoid mater). Surrounding the spinal cord in the bony vertebral column are three membranes.

From innermost to outermost, these membranes are: the pia mater, the arachnoid mater and the dura mater. The pia mater is a highly vascular membrane that closely invests in the spinal cord and the brain. The arachnoid mater is a delicate, nonvascular membrane that functions as the principal barrier to drugs crossing into and out of the CSF.
The dura mater is the outermost of the 3 layers. The space between the pia mater and the arachnoid mater is termed as the subarachnoid or intrathecal space. Approximately 500 mL of CSF is produced daily by the choroid plexuses of the cerebral ventricles, with 30 to 80 mL occupying the subarachnoid space from T11-T12 downward. The spinal cord is continuous with the brainstem proximally and terminates distally in the conus medullaris as the filum terminale, which is the fibrous extension, and the cauda equine, which is the neural extension.

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15
Q

A 37-year-old woman with pancreatic cancer comes in for a celiac plexus block. A feared complication from this block is paraplegia due to injury to the arteria medullaris magna anterior. While this artery has a variable origin, where is it most commonly found?

A. T5-T8
B. T9-T12
C. L1-L5
D. S1-S3

A

A celiac plexus block can be useful for patients with pain caused by pancreatic or other cancers arising from between the lower esophagus to the spleen. The celiac plexus lies anterior to the aorta near the celiac artery and the location can vary from T12 to L2. Under fluoroscopy a radiocontrast dye is used to confirm location, the local anesthetic can be placed after aspiration to exclude possible intrathecal or intravascular placement. After 20 minutes, pain relief should be evaluated along with motor function and a neurolytic agent can be used. Common side effects are soreness and bruising. Orthostatic hypotension can occur along with increased gastrointestinal motility secondary to the sympathectomy. The most feared complication would be an injury to the arteria medullaris magna anterior, otherwise known as the artery of Adamkiewicz, most commonly arises between T9-T12 in 60% of patients.

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16
Q

Anesthesia is induced and the LMA is easily inserted. To ensure proper placement of the LMA, the anesthesiologist pushes the LMA until it comes to a stop at what structure?

A. Thyroid Cartilage
B. Cricopharyngeus Muscle
C. Cricoid Cartilage
D. Vocal Cords

A

A is incorrect because the thyroid cartilage sits superior and anterior to the anatomic site where the laryngeal mask airway rests.
B is correct because the cricopharyngeus represents the deepest a laryngeal mask airway can reach. You go to this point and are forced to stop. This places the laryngeal mask airway in the ideal spot: facing forward so the openings face the vocal cords for optimum ventilation.
C is incorrect because the cricoid cartilage is in the trachea, the laryngeal mask airway sits in the posterior pharynx and does not, physically cannot, enter the trachea.
D is incorrect because if you stopped at the vocal cords, the laryngeal mask airway would have unstable seating and there would be a large air leak.

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17
Q

Which of the following statements best describes the anatomic features associated with a lower extremity block?

A. Lumbar plexus is formed by the anterior rami of the first three lumbar nerves
B. Lumbar plexus lies between the psoas major and quadratus lumborum muscles
C. The sciatic nerve is a combination of the tibial and deep peroneal nerve trunks
D. The posterior cutaneous nerve of the thigh is derived from the first three lumbar nerves

A

The lumbar plexus lies between the psoas major and quadratus lumborum muscles in the so-called psoas compartment.

The plexus is formed by the anterior rami of the first four lumbar nerves (L1-L4), frequently including a branch from T12 and occasionally from L5. The psoas compartment block uses a technique in which a needle is placed into this space between the psoas major and quadratus lumborum muscles.

The sciatic nerve is a combination of two major nerve trunks, the tibial (i.e., ventral branches of the anterior rami of L4-S3) and the common peroneal (i.e., dorsal branches of the anterior rami of L4-S3), which form the sciatic nerve. The trunks separate at or above the popliteal fossa, with the tibial nerve passing medially and the common peroneal laterally.

The posterior cutaneous nerve of the thigh is derived from the first, second, and third sacral nerves (S1-S3).

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18
Q

Which of the following statements best describes the anatomy of brachial plexus?

A. Brachial plexus is derived from the anterior primary rami of C1-C4 cervical nerves
B. Brachial plexus consists of five trunks, three cords, and five major terminal nerves
C. The C1 and C2 nerve roots unite to form the superior trunk of the brachial plexus
D. The prevertebral fascia envelops the brachial plexus between the scalene muscles

A

The prevertebral fascia envelops the brachial plexus between the scalene muscles.

The brachial plexus is a network of nerves formed by the anterior primary rami of the fifth, sixth, seventh, and eighth cervical nerves and the first thoracic nerve (C5, C6, C7, C8, and T1), with variable contributions from the fourth cervical (C4) and the second thoracic (T2) nerves.

After leaving their intervertebral foramina, these nerves course anterolaterally and inferiorly to lie between the anterior and middle scalene muscles, which arise from the anterior and posterior tubercles of the cervical vertebra, respectively.

The prevertebral fascia invests the anterior and middle scalene muscles, fusing laterally to enclose the brachial plexus in a fascial sheath.

The brachial plexus consists of five roots, three trunks, six divisions (two per trunk), three cords, and five major terminal nerves.

The C5 and C6 nerve roots unite to form the superior (upper) trunk, C7 continues as the middle trunk, and C8 and T1 converge into the inferior (lower) trunk.

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19
Q

How could local anesthetics block larger sensory nerves more easily than smaller motor nerves with spinal anesthesia? explanation by the anatomy surface area

A

The dorsal nerve roots are organized into component bundles. The dorsal or posterior root of the spinal nerve is one of the two roots that emerge from the spinal cord. It emerges directly from the spinal cord and travels to the dorsal root ganglion. The dorsal root transmits sensory information, forming the afferent sensory root of a spinal nerve. The dorsal nerve roots are generally larger than the ventral or motor nerve roots and are organized into component bundles. This creates a much larger surface area on which the local anesthetics act, possibly explaining why larger sensory nerves are blocked more easily than smaller motor nerves. The spinal nerve roots are not uniform in size and structure, and there is considerable interindividual variability.
Lumbosacral CSF has a constant pressure of approximately 15 cm H2O, but its volume varies by patient, in part because of differences in body habitus and weight.
The adipose tissue in the epidural space diminishes with age, and this decrease may dominate the age-related changes in epidural dose requirements.

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20
Q

Brachial plexus boundiers?

A

the brachial plexus is a network of nerves formed by the anterior rami of the lower four cervical nerves (C5, C6, C7, and C8) and the first thoracic nerve (T1). This plexus extends from the spinal cord through the cervico-axillary canal in the neck, under the clavicle, over the first rib, into the axilla. It supplies sensory and motor function to the upper chest, shoulder, and upper extremity to the fingers.

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21
Q

What is the order of the tissues encountered to achieve placement of medication in the epidural space?

A. Skin, subcutaneous fat, supraspinous ligament, interspinous ligament, ligamentum flavum, epidural space, subarachnoid space
B. Skin, subcutaneous fat, posterior longitudinal ligament, interspinous ligament, ligamentum flavum, epidural space
C. Skin, subcutaneous fat, ligamentum flavum, interspinous ligament, posterior longitudinal ligament, epidural space
D. Skin, subcutaneous fat, supraspinous ligament, interspinous ligament, ligamentum flavum, epidural space.

A

There are 3 interlaminar ligaments that connect the vertebral processes together and they are the supraspinous ligament, interspinous ligament and the ligamentum flavum. The supraspinous ligament is the most superficial, vertical ligament and connects the tips of the spinous processes. The interspinous ligaments are horizontal ligaments that connect the bottom of a cephalad spinous process to the top of the caudal spinous process. The ligamentum flavum is the last ligament to pass through before reaching the epidural space.
Option A is incorrect because while this is the correct order of tissues, it includes the subarachnoid space and the question asked about placing an epidural catheter, not providing spinal analgesia.
Option B is incorrect because the supraspinous ligament is the first ligament contacted, not the posterior longitudinal ligament. The posterior longitudinal ligament is posterior to the vertebral bodies and provides stability to the vertebral column with the help of the anterior longitudinal ligament.
Option C is incorrect because the supraspinous ligament is the first ligament contacted, not the ligamentum flavum. Additionally, the posterior longitudinal ligament is not involved in the proper placement of an epidural.
Option D is the correct order of the tissues for proper placement of an epidural catheter for labor analgesia.

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22
Q

A 1-year-old girl is undergoing her 2nd cranial vault remodeling for congenital craniosynostosis. While the surgeons are extending the skin flap to expose the superior aspect of the orbits, the patient experiences a drop in HR from 92 bpm to 37 bpm. Which one of the following cranial nerves is responsible for the afferent arm of this reflex?

A. CN III
B. CN V1
C. CN V2
D. CN V3
E. CN VI
A
The oculocardiac (or trigeminovagal) reflex can occur not only during ophthalmologic surgery, where pressure or stretch on the globe or rectus muscles can elicit a response but also with traction on the periostium of the orbit during craniofacial surgery. The nerve responsible for the afferent input is the ophthalmic branch of the trigeminal nerve (V1), and the efferent output is via parasympathetic innervation of the heart by the vagus nerve. The subsequent increase in vagal tone can result in bradycardia, heart block, ventricular ectopy, or asystole. Typically, cessation of the offending action will restore normal rate and rhythm, however prophylactic or therapeutic administration of an anti-muscarinic, such as glycopyrrolate, may be warranted. It is important to note that the retrobulbar block performed for eye surgery does not always protect against the oculocardiac reflex and can precipitate the response itself.
Exacerbating factors include inadequate anesthesia, hypoxia, and hypercarbia. With regard to neuroanatomy, the branches of the trigeminal nerve emerge from the gasserian ganglion. The ophthalmic branch (V1) provides sensory innervation to the forehead and eye, the maxillary branch (V2) provides sensory innervation to the mid-face and upper jaw, and the mandibular branch (V3) provides sensory innervation to the lower jaw and motor innervation to the muscles of mastication.
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23
Q

Which of the following statements best describes the sensory innervation of the face?

A. Sensory innervation of the face is provided by the facial nerve
B. The ophthalmic nerve innervates the lower eyelid, upper lip, and anterior area of nose
C. Sensory component of the trigeminal nerve is combined in the gasserian ganglion
D. The mandibular nerve innervates the cheek, and soft and hard palates

A

The sensory component of the trigeminal nerve is combined in the gasserian ganglion. The sensory innervation of the face is under the dependence of the trigeminal nerve associated with the C2-C4 cervical nerve roots that constitute the superficial cervical plexus. The trigeminal nerve provides sensory and motor components. The sensory component is combined in the trigeminal ganglion, also known as the semilunar or gasserian ganglion. This ganglion lies in the Meckel cave, an invagination of the dura mater near the apex of the petrous part of the temporal bone in the posterior cranial fossa. Postganglionic fibers exit this ganglion to form three nerves: the ophthalmic nerve, the maxillary nerve, and the mandibular nerve. The ophthalmic nerve innervates the forehead, eyebrows, upper eyelids, and anterior area of the nose. The maxillary nerve innervates the lower eyelid, upper lip, lateral portion of the nose and nasal septum, cheek, roof of the mouth, bone, teeth, sinus of the maxilla, and soft and hard palates. The mandibular nerve provides nerve supply to the anterior two-thirds of the tongue and the skin, mucosa, teeth, and the bone of the mandible.

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24
Q

A 64-year-old woman with carotid stenosis is undergoing right carotid endarterectomy. General anesthesia and invasive monitoring were placed without problems, the surgeon has made the initial incision and is now working to place ligatures above and below the site of the endarterectomy to achieve and maintain hemostasis once the carotid artery is opened. Within 15 seconds, the heart rate drops from baseline 75 to 25 with accompanying hypotension. You quickly inform the surgeon to stop manipulation in this area. Which cranial nerve is the efferent limb of this reflex, resulting in this dangerous bradycardia?

A

Manipulation near the bifurcation of the common carotid artery will activate the carotid sinus reflex through stimulation of the carotid baroreceptors. This afferent impulse is carried via the glossopharyngeal nerve centrally and leads to activation of the efferent signals via the vagal nerve with resulting bradycardia. Significant or sustained bradycardia as observed above can be resolved by stopping surgical manipulation and treatment with an anticholinergic drug such as atropine. Local infiltration of the carotid sinus with lidocaine can also prevent activation of this reflex.

25
Q

Which of the following represents the anterior border of the lumbar epidural space?

A. Ligamentum flavum
B. Anterior longitudinal ligament
C. Posterior longitudinal ligament
D. Dura mater

A

“Posterior longitudinal ligament” is incorrect because the posterior longitudinal ligament (PLL) lies just anterior to the vertebral body.
“Ligamentum flavum” is incorrect because the flavum is posterior to the epidural space.
“Anterior longitudinal ligament” is incorrect because the anterior longitudinal ligament (ALL) is anterior to the vertebral body, not the epidural space.
“Dura mater” is correct since the dura mater separates the epidural space from the intrathecal space and is the anterior border.

26
Q

A 35-year-old patient with long-standing diabetes is admitted for treatment of a gangrenous left foot. Venous access is challenging because of his many hospitalizations, including placement of catheters for renal dialysis. Attempts at right internal jugular cannulation have failed, even with ultrasound guidance, so a left internal jugular line will now be attempted. The needle hits a vessel and straw-colored fluid is drawn back into the syringe. Which vessel was just entered?

A. Internal Jugular Vein
B. Subclavian Vein
C. Thoracic Duct
D. Thoracic Vein

A

A is incorrect because the internal jugular vein would have dark venous blood in it.
B is incorrect because if you are attempting an internal jugular line, the needle would have to go extraordinarily deep to reach all the way down to the subclavian vein. Also, the subclavian vein would yield dark venous blood.
C is correct because the thoracic duct is on the left side and does yield lymphatic fluid, which is ordinarily straw-colored. Of note, lymphatic fluid would appear white and milky if the patient had just eaten a fatty meal.
D is incorrect because you could not reach any given thoracic vein from this approach, and a vein would yield dark blood, not straw-colored fluid. Overall, most practitioners tend to avoid a left-sided approach to central lines because you can hit the thoracic duct (resulting in a chylothorax, which is extremely difficult to treat). Also, a pneumothorax is more likely on the left side, because the heart pushes the left lung cupola up higher, thus, you are more likely to hit the pleura and cause a pneumothorax.

27
Q

C/I for Neuraxial

A
Patient refusal
Bleeding diathesis
Sever hypovolemia
Elevated ICP
Infection at the site
Sever stenotic valve or ventricular outflow obstruction
28
Q

The variability of peak neuroaxial block height and regression depends mainly on

A

80% on CSF volume, other are related to volume are body habitus and weight and height

29
Q

Which spinal layer accounts for the most functional barrier of the resistance to drug medication, barrier for drug diffusion into intrathecal space when epidural drug administered

A

Arachnoid mater (non vascular membrane attached to the most outer layer which is dura).

30
Q

Failed spinal with spinal anesthesia and total spinal with epidural are

A

When drug administration into subdural space (it contains small amount of serious fluid that allows dura and arachnoid to move over each other)

Results into patchy block with epidural because of the drug volume given is high which intended for epidural but it will cause total spinal or patchy block if administered into subdural space

31
Q

Epidural space ? And boundaries ?

A

Extends from foramen magnum to sacral hiatus

Anterior: posterior ligament
Lateral: pedicles + intervertebral foramin
Posterior: ligament flavum

32
Q

PDPH risks

A

Large needles
Multiple punctures
Cutting needles (quicke)

33
Q

What’s the local anesthetic if used spinal might increase risk for nausea

A

Procaine for unexplained reason

But has lower frequency of back and leg Pain than lidocaine

34
Q

Which local if used for spinal increases risk for transit neurologic symptoms

A

Lidocaine (it’s back and leg pain without neurological symptoms despite’s it’s name)

35
Q

Why ropivacaine not used for spinal

A

Even it’s less effect on cardiac conduction but it is less potent than bupivacaine (requires 2 times dose to achieve bupi clinical effect)

36
Q

Why neostigmine not used as neuroaxial adjunct

A

Despite that it induces analgesia (by inhibits the breakdown of acetylcholine) and by releasing Nitric oxide in spinal cord

It causes nausea and prolonged motor block made it slowly acceptable clinically

37
Q

What factors effect spinal hight block?

A

Controllable factors

  • dose (volume x concentration)
  • site of injection
  • baricity
  • posture
  • Direction of laterally facing opening of spinal needle

Not controllable factors

  • volume and density of CSF
  • patient height
Factors do not effect
Adding vasoconstriction 
Coughing or beating down
Barbotage
Rate of injection
Needle bevel
Gender
Weight (unlike epidural which weight is affected)
38
Q

What local increases risk for neurotoxicity (arachnoditis) when given epidually

A

Chloroprocaine (due to preservatives)

39
Q

What local when used epidural causes less cardiac effect with less motor block

A

Ropivicaine

Due to the only local causes vasoconstriction (all other has potential for vasodilation properties )

40
Q

27-year-old man, ASA 1, sustained multiple fractures to his right foot and toes and an ankle block is performed prior to surgery via ultrasound. Which nerves are able to be blocked with a 10mL injection of local anesthetic in subcutaneous tissues if deposited from medial to lateral malleolus without redirecting the needle?

A. Deep peroneal, superficial peroneal, and sural nerves
B. Posterior tibial, sural, superficial peroneal, deep peroneal, and saphenous nerves
C. Superficial peroneal and saphenous nerves
D. Sural, saphenous and superficial peroneal nerves

A

All 5 nerves of the ankle can be blocked with an ankle block. The deep peroneal, posterior tibial and sural nerves all need separate injections while the saphenous and superficial peroneal nerves can be blocked in one motion or also blocked separately. The deep peroneal nerve is blocked by injecting lateral to the anterior tibial artery between the anterior tibialis and the extensor halluces longus tendons. The posterior tibial nerve is blocked by inserting a needle posterior to the medial malleolus. The sural nerve is blocked halfway between the Achilles and the lateral malleolus
Option A is incorrect because only the superficial peroneal nerve could be blocked with this approach. The deep peroneal nerve is deep to the inferior extensor retinaculum and the sural nerve is posterior to the lateral malleolus
Option B is incorrect as it lists all 5 nerves involved in an ankle block, not the specific ones blocked by anterior, subcutaneous injection.
Option C is the correct answer. The saphenous nerve is blocked medially and the superficial peroneal nerve is blocked laterally in the subcutaneous tissues from medial to lateral malleolus without redirecting the needle. These can also be blocked separately if desired.
Option D is incorrect because the sural nerve is not able to be blocked by injection of the anterior, subcutaneous tissues.

41
Q

A 28-year-old man is scheduled to have a superficial mass removed from the medial aspect of the thenar eminence of his left hand. The patient requests an isolated nerve block at the elbow as this worked well for a similar procedure on his other hand in the past. Which one of the following options represents the best location to inject at the elbow to provide analgesia to the nerve in question?

A. Medial to the brachial artery pulse in a fanning motion along the intercondylar line at the elbow with the arm in the anatomic position
B. Lateral to the edge of the biceps tendon at the intercondylar line advancing with the arm in anatomic position until bone is encountered and injecting in a fanning motion
C. With the arm in the anatomic position 5 cm proximal to the medial epicondyle on the dorsal aspect of the arm
D. Just medial to the biceps tendon in a fanning motion along the intercondylar line at the elbow with the arm in the anatomic position
E. Directly anterior to the medial epicondyle on the ventral aspect of the elbow with the arm in the anatomic position

A

This patient requires a median nerve block based upon the location of the superficial mass on his thenar eminence. This block may be conducted by injecting medial to the brachial artery pulse in a fanning motion along the intercondylar line at the elbow with the arm in the anatomic position. The brachial artery lies just medial to the biceps tendon at the intercondylar line and if one injects just medial to this tendon, they place the patient at risk for an intra-arterial injection.

Ulnar nerve block at elbow:
Injecting 5 cm proximal to the medial epicondyle on the dorsal aspect of the arm will block the ulnar nerve. Injecting the ulnar nerve in a more distal position closer to the medial epicondyle where it runs more superficial is associated with a high incidence of neuritis.

Radial block at elbow:
Injecting lateral to the edge of the biceps tendon at the intercondylar line advancing with the arm in anatomic position until bone is encountered and injecting in a fanning motion should block the radial nerve.

42
Q

How would spinal cause bradycardia

A

The correct answer is bradycardia. Although bradycardia is not a common complication of spinal anesthesia, it may develop in 10-15% of patients as a result of the blockade of cardioaccelerator fibers at the T1-T4 level of the spinal cord and a decrease in venous return that causes the Bezold-Jarisch reflex which is triggered by the activation of the cardiac mechanoreceptors, thus overcoming the baroreceptor reflex. Spinal anesthesia causes both arterial and venous dilatation which then leads to a decrease in afterload and a decrease in preload, respectively.
Venous pooling of blood in high capacitance vessels result in a decrease in the preload and a decrease in the right-sided filling pressures which affect the intrinsic chronotropic stretch receptors, eventually leading to a decrease in cardiac output. Since blood pressure is the product of cardiac output and peripheral resistance, a decrease in the cardiac output or a decrease in total peripheral resistance due to arteriolar vasodilation will lead to hypotension.

43
Q

A 25-year-old man undergoes a surgical procedure under epidural anesthesia at the mid-thoracic level using local anesthesia. Which of the following cardiopulmonary changes occur with local anesthetic-only epidural solution?

A. Increased peripheral vascular resistance
B. Decreased resting minute ventilation
C. Decreased stroke volume and cardiac output
D. Increased dead space

A

The correct answer is decreased stroke volume and cardiac output. Epidural anesthesia at the mid-thoracic level produces a pharmacologic sympathectomy similar to spinal anesthesia although less severe since epidural block spreads more slowly allowing autocompensation to occur. The sympathetic blockade then leads to venous and arterial dilatation. Venodilatation leads to decreased preload, right atrial filling pressures, stroke volume, and cardiac output. On the other hand, arterial dilatation leads to decreased peripheral vascular resistance and mean arterial pressure. venodilatation The decreased afterload as a result of arterial dilatation leads to increased cardiac output, provided that the preload is maintained. However, a combination of the effects of both arterial and venous dilatation leads to hypotension and decreased cardiac output because venodilatation is more dominant. Blockade to the mid-thoracic level does not have a significant effect on the minute ventilation, tidal volume, and vital capacity.

44
Q

A 50-year-old man presents with fractured ribs and hemothorax for placement of a chest tube. He will not tolerate the chest tube placement using local anesthesia infiltration by the surgeon. You are asked to administer an intercostal block to facilitate the procedure. Which of the following anesthetics results in the highest blood serum level?

A. Lidocaine
B. Prilocaine
C. Mepivacaine
D. Etidocaine
E. Bupivacaine
A

Local anesthetic mechanism of action is at the site of injection near the target nerve. Blood flow to the location of injection attenuates its effect. The length of time that the local anesthetic is exposed to the nerve without being absorbed by the blood stream, the longer its effect. Local anesthetics’ hematogenous uptake not only results in a diminished block, but also in increased plasma concentrations of the anesthetic. Intercostal injection results in the highest plasma concentration, by comparison to caudal, epidural, brachial plexus and sciatic or femoral nerve blocks.
This is the order of hematogenous absorption of local anesthetics: intravenous > intercostal > caudal epidural > lumbar epidural > brachial plexus > subcutaneous. Intercostal blocks have a direct result of the significant blood flow through the neurovascular bundle below each rib. Of all the amino-ester local anesthetics listed, mepivacaine results in the highest serum levels after intercostal injection. Mepivacaine’s maximum dose is 4.5 mg/kg (although up to 7 mg/kg if it contains epinephrine). Careful attention must be given to its administration in the intercostal location because of its tendency towards systemic absorption.

SOURCE: 1) Drasner K. “Local Anesthetics.” Miller R, Pardo M. Basics of Anesthesia. 6th Ed. Philadelphia: Elsevier, 2011. Pg 136-138.

45
Q

A 35-year-old woman is scheduled for a gynecologic surgical procedure. You decide to administer a long-acting anesthetic agent through an L3-L4 epidural catheter. Which of the following agents has the longest duration of blockade?

A. 10 mL of 0.5% bupivacaine
B. 10 mL of 3% 2-chloroprocaine with epinephrine
C. 10 mL of 2% lidocaine
D. 10 mL of 2% mepivacaine with epinephrine

A

The correct answer is bupivacaine. Bupivacaine has the longest duration of action amongst the commonly used local anesthetic agents. Epidural placement of 0.5% bupivacaine can cause blockade for at least 160 minutes to 225 minutes duration. It can be administered without the use of epinephrine since its duration of action is not significantly prolonged with adjuvant epinephrine (180-240 minutes of duration with epinephrine) as compared with epinephrine co-administered with either lidocaine or mepivacaine.
The 3% 2-chloroprocaine is incorrect because it only has an average of 45-60 minutes duration of action without epinephrine, and can be prolonged to 60-90 minutes with co-administration of epinephrine. The 2% mepivacaine with epinephrine has a duration of blockade of about 140-200 minutes, while 2% mepivacaine alone only has an average duration of blockade of 90-140 minutes. The 2% lidocaine without epinephrine causes blockade for 80-120 minutes, while co-administration with epinephrine increases its duration to 120-180 minutes.

46
Q

A thin 88-year-old woman having ankle surgery is undergoing a popliteal fossa peripheral nerve block. As you inject the local anesthetic, she develops tinnitus, perioral numbness, and a metallic taste in her mouth. Which of the following patient factors is the best predictor of risk for developing local anesthetic systemic toxicity (LAST) during regional anesthesia?

A. BMI > 60
B. Infancy or old age
C. Placing the block by landmark techniques
D. Male sex
E. Use of ultrasound
A

Systemic toxicity of local anesthetics is a result of excessive plasma concentration of the medications. High plasma concentrations of local anesthetic cause central nervous system symptoms, including circumoral numbness, facial tingling, metallic taste in the mouth, tinnitus, vertigo, and tonic-clonic seizures. In the worst-case scenario, local anesthetic systemic toxicity (LAST) can cause cardiovascular collapse. Patients at the extremes of age are at increased risk of developing LAST if there is direct injection of local anesthesia intravascularly or high systemic absorption after block placement.
Patients who have pre-existing cardiac conduction defects or ischemic heart disease are also at increased risk of LAST. Women appear to have a higher incidence of LAST reported in the literature. Lower volumes of local anesthesia are facilitated by using ultrasound guidance, and there appear to be fewer intravascular injections. However, there is not consistent data that there are fewer overall complications. Women have a higher incidence of reported cases of LAST.

SOURCE: 1) Neal JM, Bernards CM, Butterworth JF. ASRA Practice Advisory on Local Anesthetic Systemic Toxicity. Reg Anesth Pain Med 35: 152-161, 2010 2) Drasner K. “Local Anesthetics.” Miller R, Pardo M. Basics of Anesthesia. 6th Ed. Philadelphia: Elsevier, 2011. Pg 136-138.

47
Q

Which of the following is not considered a risk factor for the development of transient neurologic syndrome?

A. Choice of local anesthetic
B. Patient position during surgery
C. Age
D. Inpatient vs. outpatient status

A

Age is correct because lidocaine, lithotomy, and ambulatory surgery status have all been implicated as risk factors in the development of TNS, whereas age has no influence.

48
Q

A 26-year-old woman, G2, P1, presents at 38 weeks of her pregnancy with regular and painful uterine contractions. The contractions are occurring every 4 mins for the past 9 hours. On vaginal examination, the cervix is soft, 60% effaced, and 2 cm dilated. She is put on an epidural and observed for progression. After nine hours, her contractions are 6 mins apart, and no change in cervical dilation is noticed. What is the most likely cause of prolonged labor?

A. False labor
B. Early initiation of epidural
C. Cervical dysfunction
D. Multiparity

A

The correct answer is the early initiation of epidural. This patient is experiencing a prolonged latent phase of the first stage of labor due to the premature use of anesthesia. In multiparous women, the latent phase is considered long when it exceeds fourteen hours. The causes of prolonged latent phase include premature or excessive use of anesthesia, uterine hypotonia, fetopelvic disproportion, and uncoordinated uterine contractions.
The spinal anesthesia given during the latent phase causes a reduction in the uterine activity. The recommendations suggest the use of epidural during the active phase of labor. The contractions in false labor are not painful and are irregular; cervical changes are absent in false labor. Cervical dysfunction leads to a firm cervix with no changes in determining active labor. Multiparity is associated with a shorter latent phase.

SOURCE: Neville F. Hacker et al. Hacker and Moore’s Essentials of Obstetrics and Gynecology. 6th edition 2015. Saunders Elsevier

49
Q

An 18-year-old male receives an interscalene block for excision of lipoma of the upper arm. Which one of the following nerves and sensory distributions is most likely to be spared?

A. The first intercostal brachial nerve/lateral aspect of upper arm
B. The first intercostal brachial nerve/medial aspect of upper arm
C. The first intercostal brachial nerve/posterior aspect of upper arm
D. The second intercostal brachial nerve/lateral aspect of upper arm
E. The second intercostal brachial nerve/medial aspect of upper arm

A

Being aware of which nerves and associated sensory areas are spared from a brachial plexus block is a critical component of preoperative planning for regional anesthesia. Furthermore, innervation can often be variable and overlapping. The implications of this phenomenon are that proximal blocks of plexuses can be more reliable than blockade of specific terminal nerves, and that areas of dual innervation can be spared if only one nerve is blocked. The brachial plexus consists of contributions from the anterior rami of spinal nerves C5 to T1, with variable contributions from C4 and T2.
Interscalene blocks may spare the inferior portion of the roots, providing sensation to the ulnar nerve, as well as the second intercostal brachial nerve, which lies outside of the brachial plexus. The medial aspect of the upper arm, beneath the axilla, is innervated both by the medial cutaneous nerve of the arm (a branch of the medial cord with contributions from C8 and T1), as well as the second intercostal brachial nerve, (a branch of the second intercostal nerve from T2). The first intercostal nerve has no brachial branches to the arm. Any brachial plexus block for surgery or a tourniquet involving this location of the arm may require a supplemental block, provided in the form of a skin wheal of local anesthetic in the area of second intercostal brachial nerve.

50
Q

Complications of Neuraxial

A

1) sympathectomy and hypotension
- extends six dermatoms above with spinal and at same level with epidural
- vasodilation (venous>arterial) leading to decrease preload

2) bradycardia
- due to blockade of cardioaccelators (T1-T4)
- also due to fall in RA filling -> decrease chronotropic stretch receptors

3) Decreased ERV
- secondary paralysis of abdominal muscles
- VC decreases as result decrease ERV
- all other lung volumes that depends on inspiration efforts are preserved

4) Apnea
- due to hypoprefusion to respiration center in brainstem (unrelated to phrenic blockade)

5) decreased RBF and urinary retention
6) LAST

7) subarachnoid injection
- results into higher block

8) PDPH

9) damage to conus medullaris
- cause isolated sacral dysfunction (paralysis of biceps femoris, anesthesia to post thigh, saddle area or great toe, and bowel/bladder loss)
- redirect needle if paraesthesia reported

10) infection
- s.aureas or epodermidis from anesthesiologists nose most common
- delayed presentation ~ 5 days
- back pain then redicular pain then motor/sensory deficits or sphincter dysfunction. Last stage is paralysis

11) TNS
- lidocaine, lithotomy, ambulatory surgery
- back, buttocks, thighs pain mirror distribution of cauda equaina

12) Neuraxial hematoma
- more sudden presentation than abscess
- sharp back pain and leg pain with progression of sensory and motor dysfunction

51
Q

RF for PDPH

A
Young femal
Large needle
Cutting needles
Pregnancy
Multiple punctures

Continues spinal or timing of ambulation are not RF

52
Q

TAP block landmarks

A

Iliac crest
Mid axillary line
Costal margins

Local dumped between IO and transverse

53
Q

Complications of TAP

A

LATS
Abdominal organ injury
Localized swelling
Femoral nerve block
- tracking local btw transverse and transversalis fascia which contains femoral nerve
- all ambulatory ptn should examined first femoral nerve block before discharge after TAP block

54
Q

Brachial plexus anatomy

A

brachial plexus is formed by the anterior rami of C5, C6, C7, C8 and T1 (the 5 roots) which merge to form 3 trunks. Each trunk splits into 2 to form 6 divisions. These 6 divisions regroup to form 3 cords. Finally terminal nerves branch from the cords.

55
Q

Celiac plexus organs at injury risk?

A

celiac plexus contains visceral afferent and efferent fibers derived from T5-T12 and lies near the L1 vertebral body. Blocking these 1-5 ganglia may be useful in patients who are experiencing visceral abdominal pain related to cancer or other causes. A solid understanding of the anatomy surrounding this plexus is necessary to limit damage to surrounding structures. The L1 vertebral body typically lies posterior to the plexus while the pancreas lies anterior. The aorta lies immediately to the left of the plexus while the inferior vena cava lies slightly anterior and to the right. The kidneys lie slightly more laterally to the plexus than the vascular structures putting them at risk for accidental puncture as well.

56
Q

A 76-year-old man presents in the preop holding area and requires superficial cervical plexus block and sedation for carotid endarterectomy. In which of the following locations should local anesthetic be injected?

A. Between the anterior and middle scalene muscles
B. Anterior border of the sternocleidomastoid muscle, 2 cm inferior to the mastoid process
C. Posterior border of the sternocleidomastoid at its midpoint
D. 2 cm superior to the clavicle at the junction of the middle and medial thirds of the clavicle
E. 2 cm superior to the clavicle at the junction of the middle and lateral thirds of the clavicle

A

“Posterior border of the sternocleidomastoid at its midpoint” is correct because needle placement is well poised to capture all branches of the superficial cervical plexus.
“Between the anterior and middle scalene muscles” is incorrect because this is the location for an interscalene block.
“Anterior border of the sternocleidomastoid muscle, 2 cm inferior to the mastoid process” is incorrect as this would be in the region of the carotid artery.
“2 cm superior to the clavicle at the junction of the middle and medial thirds of the clavicle” and “2 cm superior to the clavicle at the junction of the middle and lateral thirds of the clavicle” are incorrect as they are too inferior to capture the cervical plexus.

57
Q

A 49-year-old man with long standing Type I diabetes is scheduled for outpatient knee arthroscopy and you are considering a spinal anesthetic. Review of systems reveals he has diabetic complications to include renal involvement (creatinine 2.1), retinopathy, and peripheral vascular disease (he can only walk a block before he gets “cramps” in his calves”). You are concerned about diabetic autonomic neuropathy and decide to evaluate his orthostatic blood pressure. What result indicates his autonomic nervous system is still functional?

A. Less than 20 mmHg systolic decrease
B. More than 10 mmHg diastolic increase
C. No Change
D. More than 10 mmHg systolic increase

A

A is correct because the difference between the standing systolic blood pressure and the supine systolic blood pressure should be less than 20 mm Hg and difference in diastolic pressures should be less than 10mmHg.
Given the longstanding nature of this patient’s diabetes, the involvement of other areas (renal, retinal, peripheral vascular), this patient is extremely unlikely to demonstrate an intact autonomic nervous system. This is of concern because if you place the spinal anesthetic and there is a precipitous drop in blood pressure, the patient has few “intact compensatory mechanisms” to help out. For example, he may be unable to generate a heart rate response to compensate for the drop in blood pressure. Also, the presence of peripheral vascular disease argues strongly for the presence of coronary disease, which may be asymptomatic due to his diabetes (silent ischemia). Answers B-D are distractors and incorrect.

58
Q

Why would MAC increases risk of LAST

A

Systemic local anesthetic toxicity occurs when the rate of clearance of local anesthetic from the circulation is reduced, leading to excessively high plasma concentrations of the drug.
A patient receiving sedation during MAC may experience respiratory depression and a subsequent rise in arterial carbon dioxide concentration. This hypercarbia will increase the cerebral blood flow and thus an increased amount of local anesthetic is delivered to the brain, thereby increasing the risk for neurotoxicity. Similarly, a patient with compromised cardiovascular function may experience a further decline in cardiac output during sedation, which may result in decreased hepatic blood flow and thus reduced metabolism of the local anesthetic, which increases the likelihood of developing toxicity.
Neurotoxicity usually occurs at lower plasma concentrations than cardiotoxicity and thus is likely to precede cardiovascular toxicity. However, cardiotoxicity may sometimes be the initial presenting feature of local anesthetic toxicity.

59
Q

Which opioid receptor responsible for nausea and vomiting?

A

While mu and kappa are often involved in decreased gastrointestinal motility and resultant constipation, stimulation of delta receptors is what may precipitate nausea and vomiting after opioid administration. Binding of opioids to delta receptors in the chemoreceptor trigger zone of the area postrema of the medulla is what induces this phenomenon.