Anatomy of the Basal Ganglia and Limbic system and Neuroimaging Flashcards

1
Q

what are the main components of the basal ganglia?

A

caudate nucleus
putamen
globus pallidus

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2
Q

what is the neostriatum/striatum made up of?

A

caudate nucleus and putamen-

they are functionally linked

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3
Q

what is the lentiform nucleus?

A

the collective name for the putamen and globes pallidus-they are anatomically linked

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4
Q

what are the main functions of the basal ganglia?

A

movement, posture and muscle tone

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5
Q

which part of the basal ganglia forms the wall of the lateral ventricle?

A

the caudate nucleus

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6
Q

what is the internal capsule?

A

a dense sheet of white matter between the caudate nucleus and the other basal ganglia nuclei. it is made up of projection fibres which are important for sending information to and from the cortex

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7
Q

where is the globes pallidus found?

A

on the inner surface of the putamen

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8
Q

what are the parts of the globes pallidus?

A

globus pallidus externus and the globus pallidus internus

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9
Q

what separates the globes pallidus externes and the putamen?

A

lateral medullary lamina

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10
Q

what separates the globes pallidus externus and globes pallidus internus?

A

the medial medullary lamina

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11
Q

what are the 2 parts of the substantia nigra?

A

pars compact and pars reticulata

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12
Q

what is the blood supply of the internal capsule and basal ganglia?

A

lenticostriate arteries which arise from the middle cerebral artery

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13
Q

what is the function of the motor loops of the basal ganglia?

A

they facilitate appropriate and required movements and inhibit inappropriate movements

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14
Q

what effect do neurones from the globus pallidus internus and substantia nigra pars reticulata have on the thalamus?

A

inhibitory

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15
Q

what happens to the motor loops in Huntington’s disease?

A

there is attrition of neurones that project to the G.P internus, which results in it not being inhibited so the sub thalamic nucleus is inhibited and unwanted movements can occur

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16
Q

what is the function of the limbic system?

A

emotions
motivational behaviour
learning and memory

17
Q

what are the input nuclei of the basal ganglia?

A

caudate nucleus and putamen (striatum)

18
Q

what are the intrinsic nuclei of the basal ganglia?

A

globus pallidus externus
sub thalamic nucleus
substantia nigra pars compacta

19
Q

what are the output nuclei of the basal ganglia?

A

globus pallidus internus

substantia nigra pars reticulata

20
Q

what are some the key structures of the limbic system?

A

hippocampus
hypothalamus
amygdala
thalamus

21
Q

what is the fornix?

A

links the hippocampus to the mammillary body of the hypothalamus

22
Q

which structures for the lateral wall of the third ventricle?

A

the thalamus and hypothalamus

23
Q

where is the amygdala found?

A

in the temporal lobe between the inferior hormone of the lateral ventricle and the lentiform nucleus

24
Q

which type of memory is the hippocampus involved in?

A

declarative memory

25
Q

how is information sent from the association cortices to the limbic system?

A

the parahippocampal gyrus

26
Q

what is a PET scan?

A

positron emission tomography
a radioactive tracer is injected into the patient and accumulates in tissue, this gives off photons which are detected and used to produce an image

27
Q

what is a SPECT scan?

A

radioactive tracer injected I.V, tracer taken up in brain and emits gamma radiation which is picked up and used to produce an image