Anatomy of the adrenal gland Flashcards

1
Q

Where are the adrenal glands located

A

Superior to the kidneys in the renal fascia and posterior to parts of the diaphragm

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2
Q

What is the right adrenal gland behind

A

Liver and IVC

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3
Q

What is the left adrenal gland behind

A

Stomach and pancreas

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4
Q

How many layers does the outer cortex have

A

3

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5
Q

What is the embryological origin of the outer cortex

A

Mesoderm

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6
Q

What does the outer cortex of the adrenal gland secrete

A

Steroid hormones with cholesterol precursors

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7
Q

What is secretion of the outer cortex controlled by

A

Pituitary

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8
Q

What is the inner medulla of the adrenal gland derived from

A

Neural crest

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9
Q

What does the inner medulla of the adrenal gland secrete

A

Catecholamines: adrenaline and noradrenaline

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10
Q

What control is the secretion of the inner medulla of the adrenal gland under

A

SNS control- augments the SNS response

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11
Q

What is blood supply of the adrenal glands from and where do they come from

A

3 suprarenal each side

  • Superior (from phrenic)
  • Middle (from AA)
  • Inferior (from renal arteries)
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12
Q

What is the venous supply of the adrenal glands and what do they drain into

A

1 each side-
Right-IVC
Left-left renal vein

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13
Q

What is Addison’s disease

A

Hypoadrenalism (no secretion of any hormones)

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14
Q

What is Conn’s syndrome

A

Hyperadrenamism: Oversecretion of mineralocorticoids

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15
Q

What is Cushing’s syndrome

A

Hyperadrenalism

Oversecretion of glucocorticoids

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16
Q

What is pheochromocytoma and what does it produce excess of

A

Rare cause of secondary hypertension
-MOstly benign adrenal tumour of neuroectodermal origin

–> Produces excess catecholamines

17
Q

Symptoms of pheochromocytoma

A

headache (severe)

excessive sweating and palpitations

18
Q

How to diagnose pheochromocytoma

A

Urinary catecholamines or metabolites (not usually plasma)