Anatomy Exam 1 Flashcards
Which epidermal cell functions as an antigen presenting cell? A. Keratinocyte B. Langerhans cell C. Merkel cell D. Melanocyte
B. Langerhans cell
In skin, the integrity of the epidermis and the basement membrane is dependent on all of the following, EXCEPT A. tight junctions. B. laminin 5. C. desmosomes. D. hemidesmosomes. E. collagen VII.
A. tight junctions.
Which protein induces aggregation of tonofilaments to form keratin in the cornified layer of epidermis? A. Filaggrin B. Laminin C. Bullous pemphigoid antigen D. Elastin E. Aggrecan
A. Filaggrin
A dermatome is defined as the area of skin
A. innervated by motor branches from a single ventral root of a spinal nerve.
B. innervated by the motor branches from the ventral roots of at least two spinal nerves.
C. innervated by sensory branches from the dorsal root of a single spinal nerve.
D. innervated by sensory branches from the dorsal roots of at least two spinal
nerves.
C. innervated by sensory branches from the dorsal root of a single spinal nerve.
Which of the following histological structures/regions is equivalent to the gross anatomical "superficial fascia"? A. Epidermis B. Reticular layer of dermis C. Hypodermis D. Epimysium E. Papillary layer of dermis
C. Hypodermis
While moving into a new apartment a student lifting a heavy box of books experiences a sharp pain in his back radiating down his leg. He is diagnosed with a herniated disk at the L4 level which is compressing a spinal nerve where it exits the vertebral column. The point of compression of the nerve is the A. central canal. B. foramen magnum. C. intervertebral foramen. D. vertebral foramen. E. interspinous ligament.
C. intervertebral foramen.
Quasimoto, the "hunchback of Notre Dame," suffered from an abnormal thoracic curvature called kyphosis. In this condition the accentuated convexity of the curvature is A. anterior. B. caudal. C. lateral. D. medial. E. posterior.
E. posterior.
Epidural anesthesia is sometimes given in the final stages of labor. Which of the meninges is pierced by the needle in the delivery of the anesthetic? A. Dura mater only B. Arachnoid mater only C. Dura and arachnoid mater D. Dura, arachnoid and pia mater E. None of the meninges are pierced.
E. None of the meninges are pierced.
Which of the following is present only in spinal cord segments T1 – L2? A. Posterior funiculus B. Dorsal horn C. Central canal D. Lateral funiculus E. Lateral horn
E. Lateral horn
Which junctional complex in an epithelial cell is associated with actin microfilaments? A. Gap B. Hemidesmosome C. Desmosome D. Adherens E. Tight
D. Adherens
The pia mater of the spinal cord
A. lies immediately deep to the dura mater.
B. is punctured during a spinal tap (lumbar puncture).
C. forms the denticulate ligaments.
D. is a tough membrane composed of dense fibrous connective tissue.
E. secretes cerebrospinal fluid.
C. forms the denticulate ligaments.
Embryonic connective tissue is known as A. areolar tissue B. mesenchyme C.mesoderm D. mesothelium E.reticular tissue
B. mesenchyme
The second costal cartilage can be located by palpating the A. costal margin B. sternal angle c. sternal notch d. sternoclavicular joint e. xiphoid process
B. sternal angle
Inhibition of microtubule assembly in a neuron would interfere MOST with which of the following cellular activities?
A. Synthesis of neurotransmitters
B. A TP production
C. Packaging of neurotransmitters into vesicles
D. Axonal transport of vesicles
E. Release of neurotransmitter at the axon terminal
D. Axonal transport of vesicles
All of the following statements about elastic fibers are true EXCEPT, they are
A. found in the tunica media of the aorta.
B. branching structures.
C. composed of elastin and fibrillin.
D. found in tendons.
E. present in the dermis of the skin.
D. found in tendons.
In which of the following regions of the spinal cord would you find the most (largest area) of white matter? A. Upper cervical B. Lower cervical C. Mid-thoracic D. Lower lumbar E. Upper sacral
A. Upper cervical
The muscles of the anterior abdominal wall participate in all of the following functions
EXCEPT
A. protect the abdominal viscera.
B. move the vertebral column.
C. increase the intra-abdominal pressure.
D. extend the trunk against resistance.
E. aid in respiration and defecation.
D. extend the trunk against resistance.
Congenital muscular dystrophy is caused by a defect in the gene for laminin. Based on this
information you
would hypothesize that the loss of muscle function in this disease is due to
A. diminished Ca++ release from the sarcoplasmic reticulum.
B. a disruption in the sliding filament mechanism involving actin and myosin.
C. disruption of the internal cytoskeleton.
D. destabilization of the link to the extracellular matrix.
E. a disruption of the neuromuscular junction.
D. destabilization of the link to the extracellular matrix.
The general name for an alternative pathway of blood flow in or around an organ, around a joint, or past an obstruction is A. an arteriovenous anastomosis B. a portal system C. a perivascular plexus D. a venous plexus E. collateral circulation
E. collateral circulation
Each of the following is a is a true statement about lymphatic vessels EXCEPT
A. valves are present in lymphatic vessels.
B. lymph nodes (glands) are interposed along the course of lymphatic vessels and function to “filter” lymph.
C. blind-ended lymphatic capillaries pick up excess tissue fluid which is then known as lymph.
D. the thoracic duct is the largest lymphatic vessel.
E. lymph returns to the blood circulation when lymphatic vessels drain into arteries in the neck.
E. lymph returns to the blood circulation when lymphatic vessels drain into arteries in the neck.
In which layers of the epidermis are you most likely to see mitotically active cells? A. Stratum basale B. Stratum granulosum C. Stratum corneum D. Stratrum lucidum E. Stratum spinosum
A. Stratum basale
In both skeletal and cardiac muscle, what TWO structures are intimately associated with the release of intracellular calcium (MARK TWO ANSWERS) A. Mitochondria B. T-tubules C. Gap junctions D. Sarcoplasmic reticulum E. Endomysium
B. T-tubules
D. Sarcoplasmic reticulum
All of the following are found in the adventia of large arteries, EXCEPT A. fibroblasts B. collagen I C. nervi vasorum D. vaso vasorum E. smooth muscle
E. smooth muscle
The triceps muscle is a(n) \_\_\_\_\_\_\_ muscle innervated by the \_\_\_\_\_\_\_ nerve. A. flexor/median B. flexor/musculocutaneous C. abductor/axillary D. extensor/radial E. extensor/ulnar
D. extensor/radial
Aggrecan, a molecule found in the matrix of hyaline cartilage, is best described as a A. type of collagen. B. glycosaminoglycan. C. glycoprotein. D. proteoglycan. E. proteoglycan aggregate.
D. proteoglycan.
Desmosomes function by serving as
A. a means for communication between cells.
B. a means for attachment of adjacent cells.
C. a bridge for continuity of cytoplasm between adjacent cells.
D. a means by which tonofilaments from one cell extend into an adjacent cell.
B. a means for attachment of adjacent cells.
Autonomic nerves innervate all of the following structures EXCEPT A. heart. B. adrenal medulla. C. arector pili muscle. D. biceps brachii. E. small intestine.
D. biceps brachii.
Juvenile Paget's disease is characterized by rapidly remodeling woven bone, osteopenia, fractures, and progressive skeletal deformity. The molecular basis is not known, but osteoprotegerin deficiency could explain juvenile Paget's disease because osteoprotegerin A. is a decoy for RANKL. B. inhibits calcitonin. C. inhibits monocyte recruitment. D. blocks osteopontin. E. mimics RANKL.
A. is a decoy for RANKL.
A simple epithelium lines all of the following EXCEPT A. blood vessels. B. esophagus. C. small intestine. D. lymphatic vessels. E. trachea.
B. esophagus.
All of the following are typically seen in an axon terminal (terminal bouton) EXCEPT A. microtubules. B. vesicles containing neurotransmitter. C. intermediate filaments. D. mitochondria. E. rough endoplasmic reticulum.
E. rough endoplasmic reticulum.
Surgical approach to the abdomen sometimes requires a midline incision between the two rectus sheathes, i.e., through the A. inguinal ligament. B. arcuate line. C. linea alba. D. sternum. E. iliac crest.
C. linea alba.
In the kidney, the proximal convoluted tubule is responsible for the reabsorption of 70% of
the H2O and Na+, as well as all of the glucose and amino acids in the initial ultrafiltrate.
Which of the following intracellular organelles or cell surface specializations would you expect to be especially prominent in these cells?
A. Cilia
B. Microvilli
C. Smooth endoplasmic reticulum
D. Secretory granules
E. Lysosomes
B. Microvilli
Astrocytes are to neuronal cell bodies in the ventral horn of the spinal cord, as \_\_\_\_\_\_\_\_\_\_ are to neuronal cell bodies in a dorsal root ganglion? A. Satellite cells B. Oligodendrocytes C. Schwann cells D. Microglia E. Ependymal cells
A. Satellite cells
In the dermis, blood flow to the papillary plexus and superficial capillary loops from the deeper, subcutaneous blood vessels is regulated by the function of A. pericytes. B. arrector pili muscles. C. arteriovenous shunts . D. parasympathetic nerves to the skin. E. sensory cutaneous nerves to the skin.
C. arteriovenous shunts .
Postganglionic sympathetic fibers, which innervate sweat glands in the thoracic region, exit the sympathetic trunk to rejoin a spinal nerve via A. white communicating rami. B. gray communicating rami. C. a sympathetic nerve. D. a splanchnic nerve.
B. gray communicating rami.
The intermediate layer of back muscles functions primarily in A. respiration. B. maintenance of posture. C. movement of the upper extremity. D. movement of the lower extremity. E. movement of the head.
A. respiration.
Which of the following structures are NOT found in a stratified epithelium? A. Cytokeratins B. Hemidesmosomes C. Desmosomes D. Keratinocytes E. Tight junctions
E. Tight junctions
Individual cardiac muscle cells are mechanically linked to one another by A. Z lines. B. desmosomes. C. tight junctions. D. dense bodies. E. gap junctions.
B. desmosomes.
Which of the following are the primary curvatures of the vertebral column? A. Cervical and thoracic B. Lumbar and sacral C. Cervical and lumbar D. Thoracic and sacral
D. Thoracic and sacral
Cytokeratin is to an epithelial cell as\_\_\_\_ is to fibroblast. A. actin B. tublulin C. laminin D. desmin E. vimentin
E. vimentin
Which cells found in connective tissue are involved in host defense and the phagocytosis of cell debris, senescent red blood cells and foreign substances? A. Fibroblasts B. Macrophages C. Mast cells D. Lymphocytes E. Neutrophils
B. Macrophages
The number of vertebrae and number of spinal cord segments are the same in each region EXCEPT A. cervical B. thoracic C. lumbar D. sacral
A. cervical
Injury to smooth muscle can be repaired by the regeneration of new muscle fibers. What is the source of new smooth muscle cells? A. Smooth muscle cells B. Pericytes C. Satellite cells D. Myofibrils E. Perimysium
A. Smooth muscle cells