Anatomy and phys chapter 5 Flashcards
• Epidermis:
Superficial layer of epithelial tissue. (5 layers or strata) – Avascular – Separated from dermis by BASEMENT MEMBRANE
Dermis:
Deep layer of connective
tissue.
– Structural strength (Dense
irregular connective tissue)
Subcutaneous tissue:
Not part of skin (consist of fat)
– Loose connective tissue that
connects skin to underlying
structures
Epidermal Strata
Stratum corneum, stratum lucidum stratum granulosum stratum spinosum stratum basale
Stratum corneum -
Most superficial and consists of cornified cells
Stratum lucidum
- Thin, clear zone. Found only in palms and soles (thick skin)
Stratum granulosum
- Contains keratohyalin. In superficial layers nucleus and other
organelles degenerate and cell begins to die.
• Stratum spinosum -
Limited cell division. Desmosomes. Lamellar bodies and additional
keratin fibers
Stratum basale
Deepest portion of epidermis and single layer. High mitotic activity and
cells starts to become keratinized (keratin fiber).
Epidermal Cells
Keratinocytes
Melanocyte
Langerhan’s cells:
Merkel’s cells
• Desquamate
cells of the deeper layers undergo mitosis; as they move toward the surface,
older cells slough off.
Keratinization:
– as cells move outward through the layers they fill with keratin, die, and serve
as a layer that resists abrasion and forms impermeability layer
Keratinocytes:
most cells.
• Produce keratin for strength
Melanocytes:
contribute to skin color.
• Melanin produced by these cells then transferred to keratinocytes.
• Same number of melanocytes in all people
Sensory functions:
: pain, itch, tickle, temperature, touch, pressure, two-point discrimination.
• Meissner’s corpuscle, pacinian’s corpuscle, free nerve endings
Meissner
corpuscle fine touch
Pacinian corpuscle
responsible for deep pressure
Two Layers of the Dermis
Papillary.
– Reticular
Papillary
Superficial (outer) 1/5.
• Areolar with lots of elastic fibers.
• Dermal papillae, capillary beds. Fingerprints. Whorls of ridges.
• Touch receptors, free nerve endings sensing pain
Reticular:
Deep (inner) 4/5.
• Dense irregular C.T. Collagen and elastic fibers.
• In the figure see: some adipose, hair follicles, nerves, oil glands, ducts of sweat glands, heat
sensors, Pacinian’s Corpuscle, & arrector pili
• Determined by 3 factors:
- pigments
- blood circulating through the skin
a. Cyanosis: blue color caused by decrease in blood oxygen content - thickness of stratum corneum
Pigments
melanin
carotene
Melanin:
provides for protection against UV light. Group of chemicals derived from a.a. tyrosine.
• Colored brown to black, may be yellowish or reddish
Carotene
yellow pigment. From vegetables. Accumulates in stratum corneum, in adipose cells of
dermis, and in Subcutaneous tissue
Albinism
deficiency or absence of pigment. Production determined by genetics, hormones, exposure to
light
Thick skin
Has all 5 epithelial strata
– Found in areas subject to pressure or friction
– Palms of hands, soles of feet
– Fingerprints and footprints. Papillae of underlying dermis in parallel rows
Thin skin
More flexible than thick skin
– Lack stratum lucidum
– Covers rest of body
– Hair grows here
Callus
Increase in number of layers in stratum corneum. When this occurs over a
bony prominence, a corn forms.
Sebaceous Glands
Oily secretion (sebum) – Prevents drying and may inhibit bacteria – Most empty into hair follicle • Exceptions: lips, meibomian glands of eyelids, genitalia
• Sebaceous Glands
Oily secretion (sebum)
Physiology of the Integumentary System
protection:
- Against abrasion, sloughing off of bacteria as desquamation
occurs. (stratified squamous epithelium) - Against microorganisms and other foreign substances.
Glandular secretions bacteriostatic and skin contains cells of
the immune system (Langerhan’s cells). - Melanin against UV radiation.
- Hair on head is insulator and protection against light, and
from abrasion. Eyebrows keep sweat out of the eyes;
eyelashes protect eyes from foreign objects. Hair in nose and
ear against dust, bugs, etc. - Nails protect ends of digits, self defense.
- Acts as barrier to diffusion of water (keratin)
Classification (Depth) of Burns
• 1st degree:
damages only epidermis
– redness, slight swelling, pain
– heals within 2-3 days (usually no scar)
– includes sunburns or exposure to cold
2nd degree:
– damages epidermis and upper dermis
– redness, swelling, pain, blisters
– heals in 2 weeks with some scarring
• 3rd degree
destroys epidermis and dermis
– burned areas are cherry red to black
– nerve endings are destroyed (no pain)
– skin graft might be necessary
Burn & SurfaceArea
The Rule of 9s:
– Head (Front & Back)
9%
torso
- Front =18% (9% upper / 9% lower)
* Back = 18% (9% upper / 9% lower)
Upper limb
9% each
– Lower limb =
18% each
• Front = 9%
• Back = 9%
– Genitalia
1%
Subcutaneous (fat) tissue
Hypodermis (Subcutaneous fat)
– Superficial fascia
energy source, insulation, padding
Types of cells
Fibroblasts
– Adipose cells
– Macrophages