Anatomy Flashcards
Extracellular matrix
A substance produced by the cells of a specific tissue and can contain protein fibers, salt, water and dissolved macromolecules
Located outside of cells
Epithelial tissue
- Covers the body’s outer surface and lines it’s internal cavities
- organs are lined on the outside and inside by epithelial tissue
- the majority of glands are derived from epithelial tissue
- epithelial tissues posses little to no Extracellular matrix.
Connective tissue
Binds and support the body’s organs
Muscle tissue
Enable movement
Nervous tissue
Enables communication among the body’s organs
Characteristic of epithilial tissue
Cellularity Polarity Attachment Avascularity Innervation Regeneration
Cellularity
Composed entirely of cells with little Extracellular matrix
Cells are bound together by several types of intercellular junctions
Polarity
Epithelial cells have an apical(top or exposed) surface and a basal surface where they attach to underlying cells
Attachment
Basal surface is attached to a thin basement membrane, which is an acellular structure produced by both epithelial and underlying connective tissue cells
Avascularity
All epithelial tissue lack blood vessels, the cell receive their nutrients by diffusion from underlying tissue
Innervation
Epithilia are richly innervated to detect changes in environment at a body organ region
Regeneration
Because apical surface is constantly exposed to the environment, epithelial cells are frequently damaged or die, they are replaced as quickly as they are lost.
Functions of epithelial tissue
Physical protection
Selective permeability
Secretions
Sensations
Physical protection
From dehydration and abrasion; and physical, chemical, and biological agents.
Selective permeability
Regulates the passage of certain molecules in or out of a certain region of the body.
Secretions
Some epithelial cells called exocrine cells produce secretions such as sweat or oil.
Sensation
Posses nerve endings that can detect light, taste, sound, smell, and hearing.
Basement membrane
- A specialized structure of epithelium
- found between the epithelium and underlying connective tissue
- provides physical support and anchoring of epithelial tissue
- acts as a barrier to regulate passage of large molecules between epithelium and underlying connective tissue.
Epithelial cell layers
- simple epithelium
- stratified epithelium
- pseudo stratified epithelium
Simple epithelium
A single layer of cells with all cells having an apical surface and attached to the basement membrane.
Stratified epithelium
- Two or more layers of cells
- not all cells have an apical surface nor do all cells attach to the basement membrane.
Pseudostartified epithelium
-single layer but not all cells reach the apical surface and their nuclei give the appearance of multilayered, stratified epithelium.. But they are not
Epithelial cell shapes
- squamous
- cuboidal
- columnar
Squamous
Flattened and similar to the shape of a fried egg.
Cuboidal
About the same size on all sides, the nucleus is usually centrally located.
Columnar
Taller than they are wide and nucleus is oval and located in the basal region of the cell.
Simple squamous epithelium structure
Single later of flat cells
Simple squamous epithelium function
Rapid diffusion and some secretion in serous membranes
Simple squamous epithelium location
- lining of alveoli of lungs
- lining of blood vessels-called “endothelium”-only component of walls of capillaries
- lining of heart-called “endocardium”
- serous membranes of body cavities
Simple cuboidal epithelium structure
Single layer of cube shaped cells
Simple cuboidal epithelium function
Absorption and secretion
Simple cuboidal epithelium location
Thyroid gland follicles, kidney tubules, ducts and secretory regions of most glands
Simple columnar epithelium structure
Single layer of cells that are taller than they are wide, oval shaped nucleus near base of cell, apical regions have microvilli, may contain goblet cells that secrete mucin
Simple columnar epithelium function
Absorption and secretion, secretion of mucin
Simple columnar epithelium location
Lining of most digestive tract
Simple columnar ciliated epithelium structure
Same as non-ciliated columnar epithelium except that cells have cilia on their apical surface
Simple columnar ciliated epithelium function
Secretion of mucin, movement of mucus along apical surface by action of cilia, movement of oocyte through urine tube
Simple columnar ciliated epithelium location
Larger bronchioles of respiratory tract, lining of uterine tube
Structure of Stratified squamous epithelium-nonkeratinized
-multiple layers of cells, named for appearance of apical cells that are squamous
Function of stratified squamous epithelium-nonkeratinized
Protection against abrasion
Location of stratified squamous epithelium-nonkeratinized
Lining of oral cavity, esophagus, vagina, anus
Structure of stratified squamous epithelium-keratinized
Multiple layers of cells
More superficial cells are dead
Lack nuclei
Filled with protein keratin