Anatomy Flashcards
Location of the heart in the mediastinum
Middle mediastinum, within the fibrous pericardium.
Layers of the heart wall
Inner –> Outer
Endocardium
Myocardium
Epicardium
Endocardium composition
SIMPLE SQUAMOUS EPITHELIUM sitting on BASEMENT MEMBRANE sitting on CONNECTIVE TISSUE
Endocardium Function/Location
Lines heart chambers,
Forms valves
Myocardium composition
Cardiac muscle
Myocardium fibre orientation
Muscle bundles are orientated in different planes to be able to close down on the chamber lumen
Epicardium Composition
(nearest to pericardial cavity) SIMPLE SQUAMOUS EPITHELIUM* BASEMENT MEMBRANE CONNECTIVE TISSUE (nearest to myocardium)
Contains main branches of coronary arteries
*= visceral layer of serous pericardium
Blood enters the coronary arteries during…
Diastole - when myocardium relaxes.
at systole the openings are shielded by aortic valve cusps
Basic structure of a blood vessel
layers inside –> outside
Tunica intima,
Tunica media,
Tunica adventitia/externa
Tunica intima composition
Simple squamous epithelium,
Basement membrane,
Connective tissue
Tunica media composition
Smooth muscle,
Elastic tissue
Tunical adventitia/ externa composition
Fibrous connective tissue
Structure of elastic arteries
Many layers/ laminae of elastic fibres in T. media.
Thick T. intima
Thinner T. adventitia
Conducting arteries
Structure of muscular arteries
Thick T. media with much smooth muscle
Thick T. adeventitia (w/ vasa vasorum)
Elastic fibres concentrated in the internal and external elastic laminae (very prominent)
Distributing arteries
Structure of arterioles
No elastic fibres.
1-2 layers smooth muscle in T. media.
Rich sympathetic nerve innervation ( to regulate regional distribution of blood)
No T. adventitia
General structure of capillaries
Very thin walled, only T. intima.
Pericytes (incomplete layer of contractile cells surrounding BM that control flow)
Continuous capillaries
Material must pass through/ between cells or in selective transport mechanisms.
Can control what is exchanged.
e.g. in muscle
Fenestrated capillaries
Have fenestrations (pores).
sometimes have protein diaphragms that can filter molecules by M/W or charge
e.g. endocrine glands, kidney renal corpuscle
Discontinuous capillaries
Have gaps between endothelial cells and basement membrane cells (allows free passage of fluids and cells)
e.g. liver, spleen, bone marrow
Sinusoids
Large diameter discontinuous capillaries used for large amounts of exchange.
T. intima contains phagocytic cells.
e.g. liver, some endocrine glands
Structure of veins
Thin T. intima.
IEL, OEL and T. media thin or absent.
Thick T. adventitia = collagenous tissue.
Valves to prevent backflow
thicker wall in more superficial veins as no surrounding support.
Arteriovenous shunts
Vessels that bypass capillary beds.
E.g. in skin for thermoregulation.
Posterior border of the superior mediastinum
T1 - T4
Surface marking of apex beat
5th intercostal space, left mid-clavicular line
Heart chamber at the right border
Right Atrium
Heart chamber at left border
Left Ventricle
Heart chamber at inferior border
Right Ventricle
Heart chambers at superior border
Left and Right Atria
Heart chamber forming the anterior/sternocostal surface
Right Ventricle
Heart chamber forming posterior surface/ base of heart
Left atrium
Heart chamber forming inferior/ diaphragmatic surface of heart
Left ventricle
The heart is anterior to which vertebrae
T5 - T8
Vertebral level of the aortic arch
T4
Vertebral level of the bifurcation of the abdominal aorta
+what does it form
L4
Forms the common iliac arteries
Vertebral level of the bifurcation of the common iliac arteries
+what do they form
L5
Forms the internal and external iliac arteries
Branches of the descending thoracic aorta
Bronchial arteries,
Oesophageal arteries,
Pericardial arteries,
Posterior intercostal arteries*
*Only these are identifiable
Tributaries of the superior vena cava
Left and right brachiocephalic veins,
Azygous vein
Tributaries of the inferior vena cava
Left and right common iliac veins
Branches of the aortic arch
ascending to descending
- Bracheocephalic artery/trunk
(splits into right common carotid and right subclavian arteries) - Left common carotid artery
- Left subclavian artery
Hemiazygous vein drains into the azygous vein at vertebral level
T8/9
hemiazygous comes from the left
Name progression of main artery in arm
Subclavian,
Axillary,
Brachial,
Radial + Ulnar
The subclavian artery becomes the axilla at…
The lateral border of the 1st rib
The brachial artery bifurcates at the…
cubital fossa (inside elbow)
Ultimate venous drainage of the limbs
Superficial veins drain into deep veins and then into the inferior/ superior vena cava
The posterior tibial artery enters the sole of the foot…
where it can be palpated
inferior to the medial malleolus
Layers covering the heart
inside to outside
Visceral serous pericardium (epicardium),
(pericardial cavity)
Parietal serous pericardium,
Fibrous pericardium
Protective role of the fibrous pericardium
Prevents the heart from overfilling with blood
Innervation of the parietal serous and fibrous pericardium
Phrenic nerve
+ pain fibres
Autonomic + sensory innervation of the visceral pericardium and heart wall
(nerves and route)
Motor fibres travel via the cardiac plexus to…
Spinal cord segments T1 - T4 (sympathetic)*
+ vagus nerve (parasympathetic)
Where they innervate the AV and SA node
(*Sensory and pain fibres from the heart travel back to spinal cord levels T1-T4 in these sympathetic fibres)