Anatomy 2 Flashcards
What is the anterolateral system (also called the Lateral Spinothalamic Tract) of the spinal cord?
An ascending somatosensory pathway carrying information regarding pain and thermal sensations
What is the blood-brain barrier?
The tight junctions in the endothelial cells that line the capillaries of the central nervous system which prevent most macromolecules from entering or leaving the central nervous system
The outer 2-4 mm of the cortex is made up of gray matter that has been divided into how many horizontal layers?
6
What is contained in the dorsal root ganglia?
Cell bodies for the sensory axons of the spinal nerves
The fasciculus gracilis and fasciculus cuneatus are located in the…
Dorsal white columns
What is the name of the structure which made from the pia extending through the cauda equina from the conus medullaris to the end of the dural sac around the spinal cord, and anchoring the spinal cord in the area of the the coccyx?
Filum terminale
Are action potentials a local and graded response?
No
What are the ABCDE’s of melanomas?
A: Asymmetry
B: Borders that are uneven vs smooth
C: Color variety or change
D: Diameter that is relatively large
E: Evolving, changing in size, shape, elevation, color, etc.
Where are pseudo-unipolar cells found?
Dorsal root fibers with the dorsal root ganglia
Which artery supplies blood to the area of the superior temporal gyrus and lateral fissure, including the area of the primary auditory cortex?
Middle cerebral artery
How does CSF flow?
CSF is produced by choroid plexus and flows from the 2 lateral ventricles through the interventricular foramina to the third ventricle and then through the cerebral aqueduct to the fourth ventricle and then out into the subarachnoid space
What is the specific name of the condition caused when there is an occlusion of the foramina of the 4th ventricle resulting in a build-up of CSF within the ventricles that cannot escape into the subarachnoid space to circulate and be reabsorbed?
Noncommunicating hydrocephalus
What type of cells form myelin on the axons in the peripheral nervous system?
Schwann cells
How is the circle of willis formed?
The circle of willis is formed due to both of the posterior communicating arteries and the anterior communicating artery. The posterior communicating arteries connect the internal carotid to the posterior cerebral artery on both sides of the brainstem. The anterior communicating artery connects the two anterior cerebral arteries. The communicating arteries usually only have a little blood flow, or none at all, and their main function is to equalize pressure and shunt blood over to another artery if there is an occlusion
What is a dermatome?
An area of skin supplied by a single afferent spinal nerve (from a single dorsal root)
Where are the dorsal root ganglia located?
In the peripheral nervous system just outside of the dorsal side of the spinal cord and vertebrae
Which type of proprioceptors detect/measure muscle length?
Muscle spindles
What are golgi tendon organs?
What is the action of the sodium-potassium pump?
To actively pump 3 sodium (Na+) ions out of the cell and 2 potassium (K+) ions into the cell to maintain the correct balance for the resting membrane potential
What are the names of the major arteries that bring blood from the heart to the central nervous system (coming off of the aorta and subclavian arteries)?
Carotid arteries (internal carotid to CNS) and vertebral arteries
Where is Rexed’s lamina II (two) in the spinal cord located?
In the dorsal gray horns
Separations in the layers of the dura form cavities which are part of the drainage system of the brain and are known as…
Venous sinuses
True or False: One oligodendrocyte can extend to 20 or more axons to envelope them, forming the myelin sheath
True
During embryologic development, six hillocks of tissue form around both sides of the first branchial groove. What do these hillocks eventually become?
The pinna
During embryological development of the central nervous system, which secondary vesicle of the neural tube becomes the pons, cerebellum and a portion of the fourth ventricle?
Metencephalon
What is CN V?
Trigeminal
Sensory information from the face and motor innervation of mastication and to the tensor tympani
What is CN VI?
Abducens
Motor control of the lateral rectus eye muscles
What is CN VII?
Facial
Sensory info from tongue through the chorda tympani and motor control for facial expression and the stapedius muscle
What is CN XI?
Accessory
Motor control of sternocleidomastoid and trapezius
What is CN XII?
Hypoglossal
Motor for intrinsic and extrinsic muscles of the tongue
What is the glossopharyngeal nerve?
Motor for pharynx and palate and taste
What is the vagus nerve?
Parasympathetic motor function for heart, lungs, etc.
And sensory
What is the trochlear nerve?
Motor control of superior oblique eye muscles
CN VIII enters or exits the brainstem at…
The pontomedullary junction or cerebellopontine angle
Which extrinsic eye muscles are innervated by CN III?
Superior rectus
Inferior rectus
Inferior oblique
Medial rectus
What is meant by the term branchiomeric nerves?
Cranial nerves that innervate branchial arch musculature such as CN V, VII, IX, X and XI
Which branchial arches play a major role in development of ear structures?
Branchial arches 1 and 2
The cerebellum is connected to the main body of the pons by 3 pairs of fiber tracts known as the…
Cerebellar peduncles
Of the cerebral cortex layers, which layer is most superficial and which is the deepest?
Layer 1 is the most superficial and 6 is the deepest
The superior and inferior colliculi are located in which area of the brainstem?
Tectum of the midbrain
Which type of degeneration involves the distal portion of the axon that has been severed from the cell body and leaves Schwann tubes that may aid in regeneration?
Orthograde degeneration
What pathway projects primarily from the primary motor cortex, decussating in the pyramids of the medulla, traveling to the lateral white columns in the spinal cord to the ventral gray horn and then innervating muscles to provide the main control of voluntary skilled movements?
Corticospinal tract
What pathway projects from the medial and lateral vestibular nuclei to the spinal cord to act upon interneurons and motor neurons to control antigravity muscles for postural control?
Vestibulospinal tracts
What is the fasciculus gracilis?
Carries somatosensory information including touch and proprioception from the lower extremities to the medulla as part of the dorsal column-medial lemniscus pathway
Intensity of a stimulus is represented by frequency modulation (rate of firing) for…
Action potentials
Embryologically, the central nervous system (including the brain and spinal cord), sense organs such as the cochlear and vestibular hair cells, and the skin are derived from which of the germ layers?
Ectoderm
What is the generic term that describes defects of the spinal cord, during embryologic development when the caudal neuropore does not properly close?
Spina bifida
Which inner ear fluid is able to flow through a duct to reach the subarachnoid space and is thought to be a derivative of CSF?
Perilymph
What is gastrulation?
The formation of the three primary germ layers
During embryologic development, which germ layer gives rise to the skeletal structures, circulation structures, meninges, and cartilage (including the ossicles and temporal bone)?
Mesoderm
Embryologically, development of the inner ear begins with formation of…
The otic placodes which are thickenings of ectoderm
Embryologically, what structures are derived from the neural tube and its tissues?
Central nervous system structures including structures such as the cerebrum, brainstem, cerebellum, ventricles and spinal cord
Which classification of nerve fibers have the slowest conduction velocity and are unmyelinated?
Group IV
The binding of a neurotramsmitter to a receptor site and depolarization of the post-synaptic cell membrane due to changes in the membrane permeability is an example of what?
Activation of ligand-gated ion channels
The two vertebral arteries merge near the pontomedullary junction to form what artery?
The basilar artery
What is the reticular formation?
Diffusely organized groups of cell bodies throughout core of the brainstem which help with integration of many types of information
Which motor pathway carries information from the reticular formation of the pons and medulla to all levels of the spinal cord to influence muscle tone in the lower extremities?
Reticulospinal tract
Where is Rexed’s lamina I (one) in the spinal cord located?
In the initial portion of the dorsal gray horns (the most dorsal layer)
What is scarpa’s ganglia?
The cell bodies of the bipolar afferent vestibular CN VIII fibers located in the internal auditory canal
Some vestibular information being carried by CN VIII and coming from the vestibular nuclei is carried to the cerebellum. What is the route and location in the cerebellum where vestibular information is processed?
Nerve fibers carrying vestibular information reach the cerebellum via the juxtarestiform body of the inferior cerebellar peduncle and the information is processed primarily in the flocculonodular lobe
A reduction in blood flow can be caused by a local, attached clot in a blood vessel caused by an atherosclerotic plaque. What is this vascular abnormality called?
Thrombosis