Anat And Cells Flashcards
What are the layers of the gut tube ?
Mucosa
Submucosa
Muscularis externa
Serosa
What is the role of the epithelial layer ?
Absorption, hormones secretion,mucus production,transport and barrier
What is the main role of the lamina Propria ?
Lymphoid
Macrophages
IgA production
What is the function of the muscularis mucosa ?
Keeps epithelium in contact with Submucosa
Helps crypt dynamic
What is found in the Submucosa ?
dense CT
Blood vessels
lymphoid tissue
Plexus
What is the type of epithelium present in the gut ?
Stratified squamous in oesophagus and distal anus
Simple columnar everywhere else
What is an enterocyte ?
Simple columnar cel of the gut tube that absorbs
What is the main specialisation characteristic of the enterocyte ?
Has Microvilli
Described as brush border
How is mucus produced and what is its function in the gut (intestines+colon)?
By Goblet cells
Protects against : friction , acidic environment , bacterial invasion
Which cell produces mucus in the stomach ?
Surface mucous cells aka Foveolar cells
Which features of the gut increases the surface area ? Where are they found ?
Microvilli Villi (small intestines ) Permanent folds (Plicae circulares) Crypts (of Lieberkuhn in intestines and colon) Temporary folds of the stomach (Rugae)
Which cells are found in crypts ?
Stem cells
Paneth cells
Enteroendocrine cells
What is the function of the stem cells in crypts ?
Renew the cells of epithelium every 2-4 days
Basophilic in H&E due to mitosis
What is the function of the paneth cells of the crypts ?
Secrete antibacterial protein to protect stem cells
Eosinophils due to secretory Vesicle
What is the function of the enteroendocrine cells in crypts ?
Secrete hormones to control gut function