ANAT 100 Mod 8-10 Flashcards
What functions of the Blood?
- Helps with transporting elements throughout body, oxygen for lungs to body tissue and CO2 from body tissues to lungs
- help with body temp and PH levels
- immune responses
Four physical characteristics of blood
Viscosity
Temperature
pH levels
Volume in and individual
Viscosity
4x more viscous than water
Characteristic of blood: temp
38 C
Characteristic blood: pH levels
Ranges between 7.35-7.45
Characteristics of blood: volume
The average is 5L
Components of blood
Plasma
Formed elements
Components of blood: plasma
Accounts for 55% of total blood volume (is 92% water and 8% solutes)
Plasma solutes
Include proteins (albumin, fibrinogen, and globulin) which is 7% of blood content
Blood components formed elements three types
Erythrocytes
Thrombocytes
Leukocytes
Erythrocytes
Known as red blood cells and contain hemoglobin to transport O2 and CO2 throughout body
RBC features
- they lack nuclei
- they are 8 um in diameter and 2 um thick
- their life span is approximately 120 days
Thrombocytes
Known as platelets and are smallest formed elements of the blood. Helps stop bleeding
Features of platelets
- They lack nuclei
- they round or spindle shaped discs
- they are 2-4 um in diameter
- they originate from megakaryocytes in red bone marrow
Leukocytes
Known as white blood cells. These cells have a nucleus but do not contain hemoglobin.
Two divisions of leukocytes
Granulocytes
Agranulocytes
Five different cell types of granulocytes and agranulocytes
Monocyte
Lymphocytes
Eosinophil
Basophil
Neutrophil
Three types of granulocytes
Neutrophils
Eosinophils
Basophils
Neutrophils
- Are the most abundant cell types making up 60-70% of WBC.
- they are the first line of defence against bacterial invasion.
- they engulf bacteria and other cells
Eosinophils
Make up 2-4% of all WBC. They help defend the body against allergic reactions and parasitic infections
Basophils
- Are the least common making up only 1% of WBC
- heparin and histamine in the granules release during inflammatory or allergic reactions
Two types of agranulocytes
Lymphocytes
Monocytes
Lymphocytes
- account for 20-30% of WBC
- involved in the branch of immune system that attacks pathogens and abnormal cells
Monocytes
- account for 3-8% of WBC
- can move outside of blood vessels and into tissue
- part of immune system response
Structure of blood vessels: three tunics (layers)
Tunica externa
Tunica media
Tunica Intima
Structure of blood vessel: tunica externa
Is composed of connective tissue with collagen and elastic fibres
Structure of blood vessel: tunica media
Is composed of smooth muscle and elastic fibers
Structure of blood vessel: tunica intima
Composed of simple squamous epithelium also known as the endothelium
Two types of blood vessel cardiovascular system
Arteries
Veins
Venous system
Veins
Venule
Venous system: veins
Venule give rise to rise to small veins and then large veins
- larger lumen then arteries
- far less muscle in the tunica media compared to arteries
- veins have a one way valves that prevent blood flowing backwards
Venous system: Venule
- Smallest venues resemble capillaries structure
- smaller venules give rise to larger venules that have three thin tunics
Arterial: elastic artery
- are large arteries near the heart such as the aorta
- large lumen
- tunica media has more elastic fibers than smooth muscle
- exhibit stretching and recoil characteristics
Arterial system: muscular artery
- deliver blood to the various regions and organs of the body
- thick tunica media with a lot of smooth muscle
- exhibit contractile characteristics
Arterial system: arteriole
- Muscular arteries typically lead to large arterioles which lead to smaller ones
- large arterioles have three tunics but the media consist of only a few layers of smooth muscle
- small arterioles have single layer of smooth muscle around the tunica intima
Capillary
Smallest blood vessels and are the transition between arterioles the arterial system and venous system
- size 8-10 um
- consist only the tunica intima
The heart
- pumps blood throughout the body
- typically 30-35% of total blood volume in arterial system where 65-70% in venous system
Two types of circulation
Pulmonary
Systemic
Pulmonary circulation
Carrie’s deoxygenated blood from the heart to the lungs for oxygenation and returns oxygenated blood back from the lungs to the heart
Systemic circulation
Carrie’s oxygenated blood from heart to other organ systems/tissues of the body, except the lungs. Deoxygenated blood from tissues returns to the heart
Anatomical location of heart
- resides in the mediastinum, between lungs and thorax
- shape of heart resembles an inverted pear fruit
Coverings of the heart: two types of pericardium
Fibrous pericardium
Serous pericardium: partietal pericardium and visceral pericardium
Fibrous pericardium
Most external protective covering
Partietal and visceral pericardium
Two layers of precardial space filled with pericardial fluid. Decreases friction between the two layers when the heart beats
Four chambers of the heart
Right atrium
Left atrium
Right ventricle
Left ventricle
The atria of the heart
Receive blood from the body and lungs before blood enters the ventricles
Interatrail septum
Is the wall between the left and right atria where the fossa ovalis is found
Fossa ovalis
Is a depression in the interatrial septum of the right atrium an opening which allowed movement of blood from the right to the left atrium during fetal life
Auricles
Are extensions or pouches that project above the chambers of the left and right atria increasing the capacity of each atrium
Atrioventricular groove
Is the depression between the atria and ventricles encircling the heart also known as the coronary sulcus. It separates the atria from the ventricles externally. Also houses coronary coronary vessels
4 Valves of the heart
Tricuspid valve
Bicuspid valve
Aortic semilunar valve
Pulmonary semilunar valve
Tricuspid valve
Located between the right atrium and right ventricle also known as the atrioventriclur valve. Has structures known as chordae tendinae
Chordae tendinae
Are things strands of collagen fibres that attach to the papillary muscle
What does the tricuspid valve control
The blood flow from the right atrium into the right ventricle
Bicuspid valve
Located between the left atrium and left ventricle and is known as the left atrioventricular or mitral valve
What does the bicuspid valve control
The flow of blood from the left atrium into the left ventricle
Aortic semilunar valve located
Between the left ventricle and aorta
Aortic semilunar valve control
Blood flow from the left ventricle into the aorta
Pulmonary semilunar valve located
Between the right ventricle and pulmonary trunk
Pulmonary semilunar valve control
Blood flow from the right ventricle into the pulmonary truck
Vessels draining blood into heart
Pulmonary veins right and left
Superior vena cava
Coronary sinus
Inferior vena cava
Pulmonary veins
Drain oxygenated blood from the lungs to the left atrium
Superior vena cava
Drains the deoxygenated blood from the upper body to the right atrium
Coronary sinus
Drains the deoxygenated blood from the coronary circulation to the right atrium
Inferior vena cava
Drains deoxygenated blood from the lower body to the right atrium
Vessels pumping blood away from heart
Ascending aorta
Pulmonary trunk
Pulmonary left and right arteries
Ascending aorta
Conducts oxygenated blood from the left ventricle to the body
Pulmonary trunk
Conducts deoxygenated blood from the right ventricle to the pulmonary arteries
Left and right pulmonary arteries
Conducts deoxygenated blood from pulmonary trunk to the lungs
Flow of blood in heart
Superior and inferior vena cava
Right atrium
Tricuspid valve
Right ventricle
Pulmonary semilunar valve
Pulmonary trunk
Pulmonary arteries
Lungs
Pulmonary veins
Left atrium
Bicuspid valve
Left ventricle
Aortic semilunar valve
Aorta
Arterial supply of the heart
Right coronary artery branches
Left coronary artery branches
Three right coronary artery branches
Right coronary artery
Marginal branch
Posterior interventricular branch
Left coronary artery branches
Left coronary artery
Circumflex
Anterior interventricular branch
Veins that transport deoxygenated blood from coronary system
Small cardiac vein
Coronary sinus
Great cardiac vein
Middle cardiac vein
Breathings two cyclic phases
Inspiration
Expiration
Inspiration?
Draws oxygen rich air into the lungs
Expiration
Forces oxygen poor air out of the lungs
Functions of the respiratory system
Gas exchange
Gas conditioning
Sound production
Olfaction
Defense
Gas exchange external respiration
- Refers to the exchange of gases between the air and blood
- inspired O2 moves across the cellular membrane of the alveolous of the lung to capillaries into blood
- waste co2 moves the opposite direction and out of the body through expiration
Gas exchange internal respiration
Exchanges gases 02 and co2 between blood and cells of the body
Gas conditioning
- Need to be warmed/cleaned to prevent damage in lungs
- occurs in the nasal cavities and paranasal sinuses is swirled around becoming warm.
- air is cleansed through contact with mucosal lining of the respiratory epithelium
Sound production: respiratory system
Occurs by forceful expiration of air through the vocal cords in the larynx causing vibration
Respiratory system: olfaction
The olfactory epithelium covers the top of the nasal cavity receptors for sense of smell
Respiratory system: Defense
Coarse hairs of the nostrils, ciliated cells, mucus lining help trap particles and microorganisms from entering the nose and respiratory system
Two respiratory tract epithelium
Pseudostratified ciliated columnar
Goblet mucus cells
Pseudostratified ciliated columnar epithelium
Small fingerlike increase surface area of conditioning air
Also functions to trap inhaled particles and microorganisms caught in mucus and sweep them back up the respiratory tract
Goblet mucus cells
Found interspersed throughout Pseudostratified epithelium and traps particulate matter or microorganisms that may be inhaled. Also provides moisture before it reaches lungs
Two regions of the respiratory systems
Conducting portion
Respiratory portion
Structures of conducting potion
Nose and nasal cavity
Paranasal sinuses
Pharynx
Larynx
Trachea
Primary, secondary and tertiary bronchi
Terminal bronchioles
The conducting portion
Functions as transfer of inhaled air from the outside to the lung tissue
This is where air his humidified and trapping of debris occurs. No oxygen is absorbed into blood in this region
The respiratory potion structures
Respiratory bronchioles
Alveolar ducts
Alveolar sacs
Alveoli
The respiratory portion function
Transfers gases between the lungs and pulmonary capillaries
Facilitate the movement of gases from air to blood
The paranasal sinuses
Are a collection of air filled spaces within the bones of the skull
Aid in conditioning of air, defence
Act as a resonance chambers