Anaphylaxis

Question 1

What is biphasic anaphylaxis

Answer 1

Another anaphylaxic reaction with out another exposure to the stimulus despite complete recovery with 72hours of the first exposure

Question 2

What are the 5 things to consider when treating anaphylaxis

Answer 2

1) remove the trigger
2) give adrenaline
3) consider oxygen
4) dont sit or stand patient
5) consider fluid

Question 3

What is refactory anaphylaxis

Answer 3

No improvement despite 2 appropriate IM adrenaline doses and efficient treatment

Question 4

What antibodies activate mast cells and basophils to realise a histamine response

Answer 4

Antigen boind IGE antibodies

Question 5

What is the does of adrenaline given

Answer 5

500 mcg

Question 6

Where are alpha 1 receptors and how does adrenaline impact these?

Answer 6

Alpha 1 is in smooth muscle, adrenaline stimulates vasoconstriction reducing capiliary leakage, swelling, reducing the chance of cardiac arrest via relative hypovolemia