Analgesics - Non-opioid Flashcards

1
Q

What are NSAIDs?

A

Non-steroidal anti-inflammatory drugs

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2
Q

Give examples of NSAIDs

A

Aspirin and ibuprofen

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3
Q

What do NSAIDs do?

A

Relieve mild pain of musculo-skeletal origins with inflammatory components.

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4
Q

How do NSAIDs work?

A

Block synthesis of prostanoids (role in inflammation and pain) by inhibiting cyclooxygenase (COX).

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5
Q

What type of pain do anti-epileptic drugs relieve?

A

Neuropathic pain

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6
Q

Give examples of anti-epileptic agents

A

Carbamazepine and gabapentin

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7
Q

What are 5HT agents used for?

A

Migraines

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8
Q

Give examples of 5HT agens

A

Sumatriptan, methysergide

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9
Q

How do 5HT agents work?

A

Act on 5HT 1B/D receptors in scalp involved with serotonin release important for processes linked to pain.

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10
Q

How does ketamine work as an analgesic?

A

NMDA channel blocker, block glutamate binding which is released with noxious peripheral stimuli.

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11
Q

What other analgesics are there?

A

Local-anaesthetics.

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