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Neurobiology > Analgesics and Anaesthetics > Flashcards

Analgesics and Anaesthetics Flashcards

1
Q

Meloxicam

A

NSAID - used in small mammals, cattle and pigs

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2
Q

Dexsamethasone

A

Steroid

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3
Q

Morphine

A

Opioids

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4
Q

Medetamidine

A

A2- agonist, cattle are sensitive

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5
Q

Bupivocaine

A

Local Anaesthetic

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6
Q

Lindocaine

A

Local Anaesthetic, used systemically as a central modulator of pain

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7
Q

Ketamine

A

NDMA antagonist
Analgesic at low doses and anaesthetic at high
Dissociative anaesthetic - doesn’t cause muscle relaxation, and all reflexes maintained, causes apneustic respiration

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8
Q

Gabapentine

A

Voltage gated Ca2+ channel blocker, anti-epileptic, used for central modulation of pain

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9
Q

Carprofen

A

NSAID - used in small mammals, cattle and horses

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10
Q

Finocoxib

A

NSAID - used in small mammals

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11
Q

Finadyne

A

NSAID - used in horses, pigs and cattle

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12
Q

Pheynlbutazone

A

NSAID - used in horses

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13
Q

Ketoprofen

A

NSAID - used in pigs

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14
Q

Methadone

A

Full opioid agonist, acts of Gi to hyperpolarise cell, injection, also acts to inhibit NDMA receptors

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15
Q

Fentanyl

A

Full opioid Mu receptor agonist, acts on Gi to hyperpolarise cell, transdermal and injection

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16
Q

Buprenorphine

A

Partial opioid agonist, acts of Gi to hyperpolarise cell, injection and oral administration

17
Q

Tramadol

A

Non-liscenced opioid agonist

18
Q

Amitrypralline

A

Tricyclic anti-depressant, used as a central modulator of pain

19
Q

NO2

A

NDMA receptor antagonist, used as a central modulator of pain

20
Q

Acepromazine

A

Phenothiazine
Inhibits a number of receptors: Dopaminergic, Histamine, A1+A2, muscarinic and serotonin
Used as a sedative / anaesthetic in Horses (also for clipping and separation of foal and mare) Dogs and Cats
Not licensed in farm animals
Causes vasovagal response and fainting in Boxers
Also antiemetic, cardioprotective and a vasodilator

21
Q

Fluonisone

A

Dopaminergic antagonist, used as a sedative often in combination with Fentanyl in Rabbits, mice, rats and guinea pigs

22
Q

Xylazine

A

A2 agonist used in sedation
Emetic in cats and dogs
Cattle particularly sensitive

23
Q

Detamidine

A

A2 agonist used in sedation

Emetic in cats and dogs

24
Q

Ramifidine

A

A2 agonist used in sedation

Emetic in cats and dogs

25
Q

Aledetomidine

A

A2 agonist used in sedation

Emetic in cats and dogs

26
Q

Dexmedetomidine

A

A2 agonist used in sedation

Emetic in cats and dogs

27
Q

Diazepam

A

Benzodiazapene, sedative and muscle relaxant - acts on GABA channels increasing frequency of opening, causes dyphoria in healthy animal however

28
Q

Midazalam

A

Benzodiazepene
Sedative and muscle relaxant through actions on GABA channel - increasing frequency of opening
Causes Dysphoria in healthy animal however

29
Q

Flumazine

A

Benzodiazepene antagonist

30
Q

Isoflurane

A

Inhaled anaesthesia, can be used in all species, vapourised with NO2 (reduces MAC ) or O2
Gaba agonist, Glycine + NMDA + N.ACh antagonist, Activates K2 channels and Leak K channels

31
Q

Halothane

A

Inhaled anaesthetic

32
Q

Sevoflurane

A

Inhaled anaesthetic

33
Q

Desflurane

A

Inhaled anaesthetic

34
Q

Xenon

A

NMDA receptor antagonist - anaesthetic

35
Q

Profolol

A

GABA agonist, used as an anaesthetic ( but no analgesic affect) In cats, dogs and foals via IV

36
Q

Etomidate

A

GABA agonist, used as an anaesthetic in cardiovasularly unstable patients, racemate mixture, only R active

37
Q

Adaptil

A

Dog appeasing pheromone, can be as a room diffuser or as a collar

38
Q

Feliway

A

Mimic feline facial pheromone

39
Q

Pherocalm

A

Used for horses, mimics pheromone produced from lactating mares, both adult and foal are sensitive

Neurobiology (1 decks)

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