analgesics 3 Flashcards

1
Q

indications of anti epileptics for analgesia

A
lancinating:
stabbing 
episodic shooting
knife like
TRIGEMINAL neuralgia
pain around the face
migrain prof
diabetic NP
postherapeutic
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2
Q

migraine prophylaxes

A

carbamezapine and valproic acid

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3
Q

what are the newer drugs

A

pregaballine and gapapentine.. less SE

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4
Q

serious SE of old anti epi

A

rash
hematological parameters
liver dysfunction
hypersesitivity

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5
Q

antidepressants as analgesics

A
facilitating the descending pathway  
chronic pain 
dysesthesia:
BURNING pain 
max effect need higher doses
becareful w/ cardio D, HoTN, prolonged QT
give nortry for elderly in the morning
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6
Q

why antidepressants causes hypotention (from net)

A

by a failure of reflex peripheral vasoconstriction

by blocking cardiovascular reflexes

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7
Q

amitryptaline as analgesic

A

given at bedtime
strong sedative
anticholinergic SE

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8
Q

doluxatine

A

SNRi
fibromylgia and diabetic NP
less SE that TCA

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9
Q

nortryptaline

A

choice for elderly .. if no cardio D c/i

in the morning (insomia)

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