ANALGESICOS OPIOIDES Flashcards

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1
Q

FENTANILO: DOSIS PREMEDICACION/ADYUVANTE REGIONAL

A

25-100 mcg/DOSIS

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2
Q

FENTANILO: DOSIS ADYUVANTE AG

A

2-20mcg/kg

INFUSION 2-10mcg/kg/h

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3
Q

FENTANILO: DOSIS INTRATECAL

A

10-25mcg

1mcg/kg EN PEDIATRICO

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4
Q

FENTANILO: DOSIS EPIDURAL

A

2-10mcg/ml DE ANESTESICO LOCAL

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5
Q

FENTANILO: DOSIS DE SEDACION/ANALGESIA

A

0.5-1mcg/kg

INFUSION 0.5-2mcg/kg/h

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6
Q

FENTANILO: DEPURACION

A

HEPATICA MEDIANTE CYP 450 3A4

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7
Q

FENTANILO: INICIO DE ACION

A

1-3 MINUTOS

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8
Q

FENTANILO: DURACION DE ACCION

A

30-60 MINUTOS

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9
Q

FENTANILO: UNION A PROTEINAS

A

84%

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10
Q

FENTANILO: POTENCIA EN RELACION CON MORFINA

A

100

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11
Q

FENTANILO: DOSIS DE INDUCCION

A

3-5mcg/kg

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12
Q

REMIFENTANILO: DOSIS DE INDUCCION

A

1mcg/kg

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13
Q

REMIFENTANILO: DOSIS ADYUVANTE AG

A

INFUSION 0.05-2 mcg/kg/min

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14
Q

REMIFENTANILO: DEPURACION

A

METABOLISMO POR ESTERASAS SANGUINEAS Y TISULARES

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15
Q

REMIFENTANILO: INICIO DE ACCION

A

0.5-1.5 MINUTOS

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16
Q

REMIFENTANILO: DURACION DE ACCION

A

4-6 MINUTOS

17
Q

REMIFENTANILO: UNION A PROTEINAS

A

70%

18
Q

REMIFENTANILO: POTENCIA EN RELACION CON MORFINA

A

80-100

19
Q

MORFINA: DOSIS SEDACION/ANALGESIA

A

2-10mg IV

PEDIATRICOS: 0.02-0.1 mg/kg

20
Q

MORFINA: DOSIS INTRATECAL

A

0.1-0.5 mg

21
Q

MORFINA: DOSIS EPIDURAL

A

2-6 mg

22
Q

MORFINA: DEPURACION

A

RENAL

METABOLITOS: MORFINA-3-GLUCURONIDO (55-75% INACTIVO)
MORFINA-6-GLUCURONIDO, ACTIVO

23
Q

MORFINA: INICIO DE ACCION

A

5-20 MINUTOS

24
Q

MORFINA: DURACION DE ACCION

A

2-3 HORAS

25
Q

MORFINA: UNION A PROTEINAS

A

20-40%

26
Q

RESPUESTA AGONISTA DEL RECEPTOR OPIOIDE MU-1

A

ANALGESIA SUPRAESPINAL
EUFORIA
MIOSIS
RETENCION URINARIA

27
Q

RESPUESTA AGONISTA DEL RECEPTOR OPIOIDE MU-2

A
ANALGESIA RAQUIDEA
DEPRESION RESPIRATORIA
BRADICARDIA
ESTREÑIMIENTO
DEPENDENCIA
28
Q

RESPUESTA AGONISTA DEL RECEPTOR OPIOIDE KAPPA

A

ANALGESIA RAQUIDEA (KAPPA-1)
ANALGESIA SUPRAESPINAL (KAPPA-2)
DISFORIA
SEDACION

29
Q

RESPUESTA AGONISTA DEL RECEPTOR OPIOIDE DELTA

A
ANALGESIA ESPINAL (DELTA-1)
ANALGESIA SUPRAESPINAL (DELTA-2)
DEPRESION RESPIRATORIA
RETENCION URINARIA
DEPENDENCIA