Analgesia in Dentistry Flashcards
When should we start systemic analgesics?
Before the LA wears off
Name examples of NSAIDs (3)
- Aspirin
- Ibuprofen
- Diclofenac
What was aspirin used for dentally
Dental + TMJ pain
What drug is used more commonly in dentistry now?
Ibuprofen
List some aspirin properties (4)
- Analgesic
- Antipyretic
- Reduces elevated temp in fever - Anti-inflammatory
- Reduces redness + swelling as well as pain at the site of injury - Anti-platelet
Function of prostaglandins
They don’t cause pain directly but they sensitise the tissues to other inflammatory products
Mechanism of action for aspirin
- Reduces production of protaglandins
- Inhibits COX1+2
- COX1 inhibition reduces platelet aggregation
List some adverse effects of aspirin (4)
- GIT problems
- Mostly on mucosal lining of stomach
- Care taken when prescribing for pts with ulcers/gastro-oesophageal reflux - Hypersensitivity
- Acute bronchospasm
- Minor skin rashes
- Care when prescribing to asthmatics - Overdose
- Hyperventilation
- Vasodilation + sweating
- Tinnitus + deafness - Aspirin burns - mucosal
- When aspirin is applied locally to oral mucosa this results in chemical burns
What groups to avoid for aspirin?
- Peptic ulceration
- Epigastric pain
- Bleeding abnormalities
- Anticoagulants
- Pregnancy/breastfeeding
- Risk of haemorrhage + jaundice in baby - Patients on steroids
- Renal/hepatic impairment
- Children under 16
- Taking other NSAIDs
What drug should not be prescribed post extraction/minor oral surgery?
Aspirin
What drug should be prescribed post operatively?
Ibuprofen
Aspirin dose for mild/moderate odontogenic or inflammatory pain?
5 day regimen
40 tablets 300mg
2 tablets 4x daily after food
NSAID prescription for a hx of previous or active peptic ulcer disease for tx of odontogenic pain?
5 day regimen to prevent gastric problems
Lansoprazole capsules
15mg
5 capsules 1 daily
OR
Gastro-resistant omeprazole capsules
20mg
5 capsules 1 daily
NEITHER are licensed for children
Ibuprofen dose for mild/moderate odontogenic post op or inflammatory pain?
5 day regimen
400mg Ibuprofen
20 tablets
1 tablet 4x daily after food
Whats the max dose of ibuprofen in adults?
2.4g