Anal Tumors

Question 1

Carcinomas

2 Characteristics

Answer 1

Epithelial tissue

Spread to lymph nodes, less via blood

Question 2

Anal Sac Apocrine Gland Adenocarcinoma

Where does it spread

Answer 2

Local lymph nodes:
Sublumbar
Abdominal (mesenteric?)

Question 3

Perianal adenoma

Answer 3

Benign

Intact male dogs; testosterone driven

Question 4

Perianal gland carcinomas

Answer 4

Malignant

Possible male predominance

Question 5

Anal Sac Carcinoma
Characteristics
Presentation

Answer 5

Malignant
Hypercalcemia (PTHrp)
Anal sac mass

Median age: 10.5 years
Breeds: Springer spaniel, dachshund, malamute, cocker spaniel, German shepherd, bassets

Question 6

Anal Sac Carcinomas

Diagnostics

Answer 6

CBC, Chemistry, UA
Thoracic Radiographs
Image abdomen (>50% metastasized to lymph nodes)

Question 7

Hypercalcemia:

Lymphoma vs Anal Sac Carcinoma

Answer 7

Patients with anal sac carcinoma not as sick as lymphoma

Anal sac carcinoma: gradual increase in Ca

Lymphoma: sudden increase in Ca

Question 8

Anal Sac Carcinomas

Surgery

Answer 8

Remove mass and nodes; debulk as much as possible

Question 9

Anal Sac Carcinomas

Radiation Therapy

Answer 9

Mass and nodes

More “curative”

Question 10

Anal Sac Carcinomas

Chemotherapy

Answer 10

Carboplatin
Tyrosine Kinase Inhibitors

Can be used as preventative
Usually do surgery with chemotherapy