Anal Masses Flashcards
Premalignant Lesions (AIN)
Clinical
Pain
Bleeding
Mass +- ulceration
Pruritus
Premalignant Lesions (AIN)
Aetiology
HPV 16,18
Premalignant Lesions (AIN)
Risk Factors
• Host
-Immunocompromised: HIV
• Contamination
- Anal intercourse - Many sexual partners
Premalignant Lesions (AIN)
Diagnosis
• Biopsy
Acetic acid -> white lesions -> biopsy
Premalignant Lesions (AIN)
Histology
• SCC
- LSIL - HSIL
Premalignant Lesions (AIN)
Prevention
Smear of anus yearly in immunocompromised patients
Anal Cancer
Clinical
Pain
Bleeding
Mass +- ulceration
Pruritus
Anal Cancer
Aetiology
HPV 16,18
Anal Cancer
Risk Factors
Host:
-Immunocompromised: HIV
Contamination:
- Anal intercourse - Many sexual partners
Anal Cancer
Diagnosis
• Biopsy
Acetic acid -> white lesions -> biopsy
Anal Cancer
Histology
Proximal (glandular epithelium): adenocarcinoma
Distal (skin): SCC; MM
Anal Cancer
Staging (TNM)
• T
- > 2cm
- 2-5cm
- > 5cm
- Local invasion
• N
- Perirectal
- Ipsilateral groin/pelvis (internal iliac)
- 1 +2 OR both sides of groin/pelvis (internal iliac)
• M
Mets
Anal Cancer
Stages
- Stage 1: confined T1
- Stage 2: confined T2,T3
- Stage 3: local invasion T4 and/or LNs (Any T, Any N)
- Stage 4: mets
Anal Cancer
Management
• Curative: T1,2,3,4
− < 1cm/doesn’t involve sphincter muscle: local resection
− All the others: Chemoradiation (nigro protol: 5-fluorouracil and mitomycin and medical radiation) if remains/recurrent: APR (abdominoperineal resection)
• Palliative: M1
Anal Cancer
Prevention
Smear of anus yearly in immunocompromised patients
Pilonidal Disease
Clinical
• Sacrococcygeal mass
- Cyst - Abscess: pain + sinus: purulent discharge
Pilonidal Disease
Epidemiology
M>F
15-40 years
Pilonidal Disease
Risk Factors
Hairy
Pilonidal Disease
Pathogenesis
Obstruction of Hair Follicles
Pilonidal Disease
Management
• Abscess
− Drainage
− Surgery
Indications
♣ failure of healing after drainage
♣ Recurrent disease
Options
Pilonidal cystotomy
Rectal Prolapse
Mucosal/Partial Thickness
Clinical
• Increased intra-abdominal pressure: straining, coughing, laughing, Valsalva
− Pain
− Blood and mucus from the anus
− +- extrusion of mass
− Persistent desire to defecate
Rectal Prolapse
Mucosal/Partial Thickness
Epidemiology
• Extremes of ages: <5 yr old and >5th decade (most common in children)
Rectal Prolapse
Mucosal/Partial Thickness
Aetiology
Primary
• Children
− Bowel more loosely attached to muscle
− Hypertrophy of the submucosal lymphoid aggregates: Peyer’s patches
Secondary
• Increased abdominal pressure
− Obesity
− Chronic cough – smoking, bronchitis
− Constipation
− Jobs requiring heavy lifting + strain
• Neurological disorders
− Spinal: trauma; non-trauma
• Muscles
− Weakened pelvic floor muscles
⎫ Obstetric trauma
⎫ Non-obstetric trauma
♣ Physical trauma e.g. pelvic fractures
♣ Radiotherapy
♣ Surgery
⎫ Menopause
⎫ Connective tissue disorders
− Weakened anal sphincter muscles
Rectal Prolapse
Mucosal/Partial Thickness
Classification
Protrusion of mucosa only
Rectal Prolapse
Mucosal/Partial Thickness
Complications
• GIT
− Permanently extruded rectum with excoriation, ulceration
− Faecal incontinence
− Strangulation + ischaemia
• Urinary
− Urinary incontinence
Rectal Prolapse
Mucosal/Partial Thickness
Diagnosis
• Ask patient to squat and cough/strain bulge
− Haemorrhoids vs rectal prolapse
⎫ Not circumferential like rectal prolapse
⎫ Can’t feel in-between haemorrhoid and skin; with rectal can feel rectal wall on top of anus
• No bulge, but suspect partial thickness prolapse -> defecating proctography
Rectal Prolapse
Mucosal/Partial Thickness
Management
• Conservative (in children)
− Reduce if possible; table sugar has been used to reduce incarcerated rectal prolapse by absorbing the edema of the rectal , thus making it easier to reduce
• Surgery (in adults)
− Perineal
-Mucosal excision
Rectal Prolapse
Full Thickness
Clinical
• Increased intra-abdominal pressure: straining, coughing, laughing, Valsalva
− Pain
− Blood and mucus from the anus
− Extrusion of mass
− Persistent desire to defecate
Rectal Prolapse
Full Thickness
Epidemiology
- Extremes of ages: <5 yr old and >5th decade (most common in adults)
- F (85%) – child birth > M
Rectal Prolapse
Full Thickness
Aetiology
Primary
• Children
− Bowel more loosely attached to muscle
− Hypertrophy of the submucosal lymphoid aggregates: Peyer’s patches
Secondary
• Increased abdominal pressure
− Obesity
− Chronic cough – smoking, bronchitis
− Constipation
− Jobs requiring heavy lifting + strain
• Neurological disorders
− Spinal: trauma; non-trauma
• Muscles
− Weakened pelvic floor muscles
⎫ Obstetric trauma
⎫ Non-obstetric trauma
♣ Physical trauma e.g. pelvic fractures
♣ Radiotherapy
♣ Surgery
⎫ Menopause
⎫ Connective tissue disorders
− Weakened anal sphincter muscles
Rectal Prolapse
Full Thickness
Classification
- External: entire rectal wall, muscle and mucosa become displaced through the anus; mucosal covering and anal skin are continuous
- Internal: internal intussusception): prolapse is internal, concealed, or occult * mucosal covering and anal skin are not continuous*
Rectal Prolapse
Full Thickness
Complications
• GIT
− Permanently extruded rectum with excoriation, ulceration
− Faecal incontinence
− Strangulation + ischaemia
• Urinary
− Urinary incontinence
Rectal Prolapse
Full Thickness
Diagnosis
• Ask patient to squat and cough/strain bulge
− Haemorrhoids vs rectal prolapse
⎫ Not circumferential like rectal prolapse
⎫ Can’t feel in-between haemorrhoid and skin; with rectal can feel rectal wall on top of anus
• No bulge, but suspect partial thickness prolapse -> defecating proctography
Rectal Prolapse
Full Thickness
Management
• Conservative
− Reduce if possible; table sugar has been used to reduce incarcerated rectal prolapse by absorbing the edema of the rectal , thus making it easier to reduce
• Surgery
− Abdominal
⎫ Transabdominal rectopexy: mobilization of the rectum and suturing to the presacral fascia
− Perineal
⎫ Delorme’s perineal rectopexy: mucosal excision with suture plication of the excessively long rectal muscle tube in an effort to shorten it)
⎫ Altemeier perineal rectal resection: rectosigmoidectomy with primary anastomosis