Anal Fissure Flashcards

1
Q

Definition

A

An elongated ulcer which occurs in the long axis of the lower anal canal.

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2
Q

Incidence

A

*Sex: males and females are equally affected. *Age: - Most common in middle aged. - Not common in elderly. - Not rare in children.

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3
Q

Etiology are

A

A-No definitive cause

B-definitive cause

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4
Q

A-No definitive cause is found in the majority postulated mechanisms are

A

*Trauma:

  • Hard stool (in constipated patients) ) injury to the least supported site, i.e., midline posterior fissure.
  • Repeated deliveries ) damage of perineal body ) loss of ant. Anal support — midline anterior fissure.

*lschemia:

  • May play a role in development of the condition.
  • Midline posterior fissurea is the most common as it is least vascular.
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5
Q

B-definitive cause is found in a minority

A

is found in a minority.

*IBD especially Crohn’s disease

*STDs

*latroqenic.

  • Large enema, endoscope.
  • Post hemorroidectomy: removal of too much skin –> stenosis –> injury of mucosa by hard stools. These fissures may be at any site & even multiple
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6
Q

pathogenesis

A

It is a vicious circle Pain is the main pathogenic factor in acute fissure)

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7
Q

Pathology I Site:

A

*Usually in the midline.

  • Midline posteriorly (90%)
  • Midline anteriorly (10oh): Especially common in multiparous females.
  • Anterior and posterior fissures may coexist.

*May be anywhere as in Crohn’s disease.

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8
Q

Pathological changes:

A

*Acute Fissure

  • Superficial tear present in the sensitive part (below dentate line) —> pain.
  • Pain —> spasm of internal sphincter —> J blood flow —> prevents healing of fissure.

*Chronic Fissure

-lf acute fissure is not treated well, it will proceed to chronic stage with secondary pathological changes:

a- Margins: become indurated, thick and fibrotic.

b- At the upper end of fissure: an anal papilla may develop.

c- At the lower end of fissure: sentinel pile (skin tag) may develop.

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9
Q

Symptoms

A
  1. Pain:
  • ls the main symptom.
  • Character: sharp, agonizing.
  • Site: localized to the anus, can radiate to the coccyx or to the genitalia.
  • Starts: at defecation.
  • Lasts: for about t hour after defecation, and ends suddenly.
  • Course: may have remissions for days or weeks.

2.Constipation:
The severe pain forces the patient to postpone defecation –> more constipation –> inc fissure (vicious circle).
3.Bleeding:
-Only a slight streak of blood (bright red) on the surface of the stool.

4.Slight anal discharqe and pruritis:
-lf an abscess forms and bursts, there will be purulent discharge.
5.Reflex svmptoms:
Burning micturition, dysmenorrhea and pain along the thighs

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10
Q

Signs ln acute anal fissure:

A
  1. ln acute anal fissure: .
    * lnspection:
  • The anal verge is tightly contracted, puckered anus.
  • lf the 2 gluteal folds are gently pulled laterally, a small tear will be seen.
  • DRE:
  • Better to be avoidedE, as it is very painful.
  • lf it is essential to exclude other pathology, it should be done under general anesthesia.
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11
Q

Signs ln Chronic anal fissure:

A
  1. in chronic fissure:
    * inspection:
  • The fissure can be seen.
  • An anal papilla or a sentinel pile may be present.
  • DRE:
  • Fissure is fibrotic & indurated (Button hole induration).
  • Sphincter is fibrosed.
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12
Q

DD

A

Of painful anal conditions

  1. Anal fissure.
  2. Perianal suppuration.
  3. Prolapsed strangulated piles.
  4. Acute perianal hematoma.
  5. Carcinoma of the anus.
  6. Proctalgia fugax (idiopathic).
  7. Crohn’s disease
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13
Q

Complications

A

1- Fissure abscess ) fistula.

2- Acquired megacolon.

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14
Q

Invetigation

A
  1. It is a clinical diagnosis, however, if multiple and in uncommon site —> Search for a specific cause e.g. Crohn’s disease —> biopsy
  2. Preoperative lnvestigations: CBC , LFTs, ….
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15
Q

ttt of acute fissure

A

(Essentially medica!, but sometimes surgery is needed)
*Life style chanqes:
-High fiber diet (fruits. vegetables & cereals).
Aim: to make stool bulky & avoid constipation
-Laxatives (e.q. lactulose syrup)
Aim: to soften the stool
-Sittinq in a warm bath after using the toilet.
Aim: relieve the spasm & pain

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16
Q

medical ttt of acute fissure

A

Medical treatment:

Chemical sphincterotomy by:
–> Glyceryl trinitrate (GTN) ointment (2-10%):

  • Mechanism: relaxes the sphincter and improves the blood flow.
  • Success rate: about 60-70%
  • Side effects: headache, recurrence after stoping treatment.

–> alternatives:

  • Ca channel blockers (diltiazem, nifedipine)
  • local injection of botulinum toxins
  • a local anesthetic ointment is introduced gentally
  • local steroids to reliefe pain and inflammation
17
Q

aim of medical ttt

A
18
Q

advantage of medical ttt

A
19
Q

surgical ttt

A
20
Q
A