Anaesthetics CBD topics Flashcards
A to E interventions of a bleeding patient
A - Clear visible secretions with suction. Maintain airway with manoeuvres or support (Guedle)
B - 15L of oxygen with a non-rebreathable mask.
C - 2x large bore cannulas. 250ml of WARM normal saline STAT. IV PPI to decrease gastric acid levels (high acid inhibits platelet aggregation and clot formation).
D - Blood sugars. GCS score.
E - urgent endoscopy.
Types of hypoxia
Hypoxic hypoxia - aspiration
Anaemia hypoxia - haemorrhage (low O2 dissolved in blood)
Histotoxic hypoxia - cyanide poisining
Stagnant hypoxia - septic shock
Bloods in haemorrhage patient
FBC, U+E, LFT, Clotting screen, Group and save.
What fluids are not used in massive haemorrhage
Ones containing glucose/dextrose. Hypertonic so goes into cells rather than stays in plasma and does not rehydrate whole body.
Problems with over fluid resuscitation
Pulmonary oedema.
Could dislodge clots
Electrolyte imbalance (hypernatraemia with normal saline or hyperkalaemia with Hartmann’s).
Aim for MAP of >65, Systolic BP of >90mmHg, HR of 100bpm.
Don’t raise BP too rapidly as won’t support stopping the bleed.
Definition of disseminated intravascular coagulation
Systemic activation go coagulation pathways leading to consumption of platelets & coagulation factors and also microthrombi from fibrin deposits. Results in end organ damage, thombocytopenia and bleeding
Causes of DIC
GI haemorrhage Placenta abruption Amniotic fluid embolism Large aortic aneurysms Major trauma Severe liver failure
Blood test results in DIC
PT (extrinsic and common coagulation pathways) - increased
Platelets - decreased
Fibrinogen - decrease
D-dimer (Evidence of plasmin-mediated biodegradation) - increased
Treatment of DIC
Treat cause.
4 units of red blood cells.
4 units of fresh frozen plasma (leave 30mins to thaw)
1 unit of platelets
Keep patient warm with warming fluids and warming blanket.
1g of tranexamic acid IV followed by 1g after 3hrs.
Can use Cryoprecipitates instead of FFP.
Rise in Hb with 1 unit of blood
1g/dl
Complications of massive transfusion
Hyperkalaemia due to cell lysis from circulatory overload.
Transfusion-related acute lung injury
Components of optimising pre-surgery
Stop smoking (aim for 6-8weeks pre-op or at least 24hrs)
Control any co-morbidities (DM, HTN, COPD)
Optimise Hb
Weight loss via nutrition and exercise.
Reduce alcohol intake.
Symptoms and risk factors of obstructive sleep apnea
Snoring during the night followed by periods of no breathe then rewatching breathe then snoring again. Daytime tiredness High blood pressure High BMI High neck circumference Over 50 Male Irritable Poor concentration Low libido
Treatment of Obstructive sleep apnoea
CPAP
Investigations of OSA
Polysynography and sleep studies.
Steroids use in surgery patients
If low steroid prescription e.g. 10mg of prednisolone - take meds as usual.
If >10mg and minor operation - oral morning dose or IV 25-50mg Hydrocortisone at induction and resume oral dose after operation.
If >10mg and major operation - IV 25-50mg Hydrocortisone at induction and 2 days of IV TDS hydrocortisone then resume oral meds.
Thromboprophylaxis in epidurals
Low molecular weight heparin.
Give dose then wait 12hrs before administering epidural. Wait 12hours after last dose before removing catheter and then a further 4 hours before next dose of LMWH.
MRI ASAP if signs of haematoma!
Management of hypoglycaemia
Img of IV glucagon or 50mg of oral glucose or 50ml of 10% dextrose IV