Anaesthetics Flashcards

1
Q

What do inotropes do?

A

increase myocardial contractility to increase cardiac output

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2
Q

What do vasopressors do?

A

increase vasoconstriction leading to increased SVR and BP

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3
Q

What type of receptor are adrenergic receptors?

A

G-protein coupled receptors

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4
Q

What do alpha 1 receptors cause?

A

smooth muscle contraction

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5
Q

Where are beta 1 receptors located?

A

heart

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6
Q

Where are beta 2 receptors located?

A

blood vessels

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7
Q

Which receptor does Noradrenaline work on?

A

alpha 1

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8
Q

Which receptor does Adrenaline work on?

A

low doses - beta

high doses - alpha

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9
Q

What receptors does Dobutamine work on? What does it cause?

A

beta 1 to increase heart rate but beta 2 to decrease SVR therefore BP

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10
Q

What do beta 2 receptor agonists cause?

A

vasodilation

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11
Q

What is the dosage of propofol?

A

1.5-2.5mg/kg

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12
Q

What does propofol do to BP and HR?

A

marked drop in both

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13
Q

What is the main indication for thiopentone?

A

RSI

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14
Q

What are the benefits of thiopentone?

A

antiepileptic properties and neuroprotective

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15
Q

What does thiopentone do to HR and BP?

A

increases HR but drops BP

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16
Q

When is thiopentone contraindicated?

A

porphyria

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17
Q

What is the dosage of ketamine?

A

1-1.5mg/kg

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18
Q

What does ketamine do to HR and BP?

A

increases both

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19
Q

What is the dosage of etomidate?

A

0.3mg/kg

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20
Q

Which induction agent has the lowest incidence of hypersensitivity?

A

etomidate

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21
Q

Which induction agent causes bronchospasm?

A

thiopentone

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22
Q

Which induction agent can cause adreno cortical suppression?

A

etomidate

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23
Q

Which muscle relaxant is depolarising?

A

suxamethonium

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24
Q

Which muscle relaxant is used in RSI?

A

suxamethonium

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25
Which muscle relaxant is associated with malignant hyperthermia?
suxamethonium
26
What is the dosage of suxamethonium?
1-1.5mg/kg
27
Which non depolarising muscle relaxant is longest acting?
pancuronium
28
Which non depolarising muscle relaxants are intermediate acting?
vecuronium, rocuronium
29
Which non depolarising muscle relaxants are slow acting?
atracurium, mivacurium
30
What is used to reverse non depolarising muscle relaxants?
neostigmine
31
What is given along with neostigmine in reversal of muscle relaxant?
glycopyrrolate
32
What is the dosage of lignocaine without adrenaline?
3mg/kg
33
What is the dosage of lignocaine with adrenaline?
7mg/kg
34
What is the dosage of bupivacaine/levobupivacaine without adrenaline?
2mg/kg
35
What is the dosage of bupivacaine/levobupivacaine with adrenaline?
2mg/kg
36
What is the dosage of prilocaine without adrenaline?
6mg/kg
37
What is the dosage of prilocaine with adrenaline?
9mg/kg
38
What is the MAC of sevoflurane?
2%
39
Which inhalational agent is used for induction?
sevoflurane
40
What is the MAC of desflurane?
6%
41
Which inhalation agent is used in longer operations?
desflurane
42
What is the MAC of isoflurane?
1.15%
43
Which inhalational agent has least effect of organ blood flow?
isoflurane
44
Which receptors does ephedrine work on?
alpha and beta
45
What is the effect of ephedrine?
rise in HR and contractility (BP)
46
What is the effect of phenylephrine?
rise in BP through vasoconstriction, drop in HR
47
Which receptors does phenylephrine work on?
alpha receptors
48
Which receptors does metaraminol work on?
predominantly alpha
49
What is the effect of metaraminol?
rise in BP through vasoconstriction
50
What is the equation for cardiac output?
CO= SV x HR
51
What is the effect of PPV on venous return to the heart?
impedes it so reducing preload and therefore CO
52
Which inhalation agent is least irritant to airways?
sevoflurane
53
What are the risks of hypothermia?
coagulopathy, perioperative cardiac events, increased risk of post op infection, prolonged recovery
54
Which level is a spinal block given?
L3/L4
55
Which level does the spinal cord end?
L1/L2
56
What does the needle have to pass through to enter the epidural space?
Subcut, supraspinous ligament, interspinous ligament, ligamentum flavum
57
Which local anaesthetic subtype is most likely to cause allergy?
esters
58
Which amides are long acting?
bupivacaine, ropivacaine
59
Which esters are short acting?
procaine, benzocaine, cocaine
60
Which amides are intermediate acting?
lidocaine, mepivacaine
61
What percentage of total body weight is water?
60%
62
What are the CEPOD categories?
immediate/emergency, urgent, expedited/scheduled, elective