Anaesthesia Flashcards
Aims of anaesthesia
Hypnosis
Analgesia
Muscle relaxation
Airway control
Endotracheal tube
or laryngeal mask airway
Maintenance
Usually volatile agent added to N2O/O2 mix
Muscle Relaxation
Depolarising: suxamethonium
Non-depolarising: vecuronium, atracurium
Induction
IV propofol
End of Anaesthesia
Change inspired gas to 100% O2
Reverse paralysis: neostigmine + atropine
(prevent muscarinic side effects)
Neostigmine
Acetylcholinesterase uptake inhibitor
Pre-medication: 7As
- Anxiolytics and Amnesia: e.g. temazepam
- Analgesics: e.g. opioids, paracetamol, NSAIDs
- Anti-emetics: e.g. ondansetron or metoclopromide 10mg
- Antacids: e.g. lansoprazole
- Anti-sialogue e.g. glycopyrolate (↓ secretions)
- Antibiotics
Regional Anaesthesia
Used for minor procedures or if unsuitable for general anaesthesia
• Nerve or spinal blocks
• Use long-acting agents: e.g. bupivacaine
Contraindications of nerve or spinal blocks
Local infection
Clotting abnormality
Complications of propofol induction
Cardiorespiratory depression
Complications of intubation
Oro-pharyngeal injury with laryngoscope or oesophageal intubation
Complications of loss of pain sensation
- Urinary retention
- Pressure necrosis
- Nerve palsies
Complications of loss of muscle power
- Corneal abrasion
* No cough → atelectasis + pneumonia
Malignant Hyperpyrexia
Rare complication of halothane or suxamethonium • Autosomal Dominant inheritance • Rapid rise in temperature + masseter spasm • Tx - dantrolene + cooling