Amylase and lipase Flashcards
Where is amylase found
Saliva and pancreatic juices
What does amylase do?
Breaks down starch into simple sugars
In a patient with raised amylase what does it suggest?
Pancreatitis
Values are normally more than 1000
Is it possible for there to be false negative with a patient with pancreatitis
yes, the amylase level is likely to return to normal after 5 days, although pancreatitis may not have resolved
What is lipase
as pancreatic triacylglycerol lipase, is secreted from the pancreas and is the primary enzyme that hydrolyses dietary fat.
When may lipase levels become elevated
In acute pancreatitis it rises after the first 48 hours and remains elevated for 5 to 7 days.
Persitantly high lipase levels may suggest
Pseudocyst formation
Falsely positive lipase levels occur in
GI obstruction, duodenal ulcer, severe gastroenteritis and cholecystitis (when it is impacting on the pancreas