AMK day teach Flashcards
what is copd
irreversible obstruction of the airways consisting of chronic bronchitis and emphysema ( hyper resonant due to expansion)
chronic bronchitis
hypertrophy an hyperplasia of mcus glands in the bronchi
emphysema
enalargemtn of airspaces due to destruction of the alveolar wall
what is the CURB65 score
confusion AMST over 8
urea over 7
repsriaotry rate over 30
lung cancer commonly metastasises to where
brain, breast, adrenals & bone.
symptoms of lung cancer
Sx: SoB + Haemoptysis + Finger clubbing + Weight loss
Cough
Enlarged supraclavicular nodes
Recurrent pneumonia
investigations for lung cancer
Ix: CXR
Hilar enlargement
“Peripheral opacity” – Visible lesion in the lung field
Pleural effusion – Unilateral in cancer
Collapse
Ectopic ACTH secretion from small cell lung cancer
most common non small cell cancers
Adenocarcinoma (~40%) Peripheral + Most likely to cause pleural effusion Non-smokers Invade mediastinal lymph nodes & pleura Squamous cell carcinoma (~20%) Central Smokers Large cell carcinoma (~10%) Other types (~10%)
small cell cancers can
Contain neurosecretory granules which can release hormones ⇒ Paraneoplastic syndrome
Lamberton-Eaton myasthenic Syndrome
99% case in smoker
Poor prognosis
Very aggressive + Early metastasis
Tx: Surgery
obstructive disease parameters
Decreased FEV1
Normal FVC
FEV1:FVC ratio <0.7
restrictive disease parameters
Decreased FEV1
Decreased FVC
FEV1:FVC ratio >0.7