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Drug monitoring > Amiodarone > Flashcards

Amiodarone Flashcards

1
Q

What is amiodarone used for?

A

Treatment of arrhythmias

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2
Q

What is the dose for amiodarone?

A

200mg TDS for 7 days
200mg BD for 7 days
200mg OD maintenance

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3
Q

Amiodarone side effects (10)

A 
N+V
Taste disturbance
Pulmonary toxicity
Reversible corneal micro-deposits
Phototoxicity
Slate grey skin
Tremor
Sleep disorder
Hypo/Hyperthyroidism
Jaundice
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4
Q

Amiodarone monitoring

A

Liver function tests before treatment, then every 6 months
Thyroid function tests before treatment, then every 6 months.
Serum potassium before treatment
Chest x-ray before treatment

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5
Q

Amiodarone Interactions

A

Warfarin: Amiodarone inhibits warfarin metabolism - enhanced anticoag

B-blockers: Increased risk of bradycardia, AV block and myocardial depression

Lithium: Risk of ventricular arrhythmias

Digoxin: Amiodarone increases Digoxin plasma conc

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6
Q

Is amiodarones half life long or short?

A

LONG - interactions can happen several weeks or months later

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Drug monitoring (7 decks)

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