Aminoglycosides Flashcards

1
Q

drugs available

A
Gentamicin
Tobramycin
Amikacin
Kanamycin (topical)
Steptomycin
Neomycin (topical)
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2
Q

aminoglycosides MOA

A

toxic but potent antibiotics. narrow therapeutic window
binds to 30S
irreversible inhibition of protein sythesis

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3
Q

aminogylcoside SOA

A

gent, tobra, net, amikacin
aerobic gram -: citrobacter, enterobacter, e.coli among others
aerobic gram +: staph
mycobacterium TB: steptomycin and amikacin
NO ANAEROBIC

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