Aminoglycosides Flashcards
1
Q
drugs available
A
Gentamicin Tobramycin Amikacin Kanamycin (topical) Steptomycin Neomycin (topical)
2
Q
aminoglycosides MOA
A
toxic but potent antibiotics. narrow therapeutic window
binds to 30S
irreversible inhibition of protein sythesis
3
Q
aminogylcoside SOA
A
gent, tobra, net, amikacin
aerobic gram -: citrobacter, enterobacter, e.coli among others
aerobic gram +: staph
mycobacterium TB: steptomycin and amikacin
NO ANAEROBIC