Aminoglycosides Flashcards
1
Q
What is the prototype for this med?
A
Gentamicin (Garamycin)
2
Q
Whats the action for this med?
A
Bactericidal, broad spectrum, disrupts protein synthesis
3
Q
What are the uses ?
A
IM/IV empirically for serious systemic infections
4
Q
What does Neomycin do?
A
Sterilizes GI tract prior to colon surgery
5
Q
What are the adverse effects ?
A
Paresthesia of extremities , Nephrotoxicity, Ototoxicity, Neurotoxicity
6
Q
Who’s more at risk for adverse effects?
A
People with hypersensitivity, caution in elderly and people with renal effects
7
Q
What labs should you monitor ?
A
Serum gentamicin drug levels
8
Q
How can you decrease toxicity?
A
once daily dosing, encourage with fluid intake, Dose no more than 10 days, Repeated doses over course of months
