AMINOGLUCOSIDOS Flashcards

1
Q

Antibióticos que pertenecen a aminoglucósidos

A

amikacina, estreptomicina, gentamicina, tobramicina, neomicina

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2
Q

mecanismo de acción

A

Se unen subunidades 30 y 50s del ribosoma y bloquean la lectura del ARN mensajero

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3
Q

describe amikacina

A

IV o IM, infecciones complicadas o graves de GRAM -

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4
Q

antibiótico exclusivo para tuberculosis

A

estreptomicina

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5
Q

describe gentamicina

A

IV o IM, infecciones complicadas o graves de GRAM+

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6
Q

describe tobramicina

A

uso inhalado, UNICO EN MONOTERAPIA, gram -, px con fibrosis quística

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7
Q

¿Para qué es a neomicina?

A

TOPICO, para gram -

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8
Q

Característica de los aminoglucósidos en cuanto a la terapia

A

NUNCA EN MONOTERAPIA

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9
Q

¿por qué no en monoterapia?

A

genera resistencia, poco poder

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10
Q

Efecto secundario mas importante

A

nefrotoxicidad

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11
Q

espectro antimicrobiano de los aminoglucósidos

A

enterobacterias y pseudomonas

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