amino acids, peptides, proteins Flashcards
what is a proteins function
transport, structure, storage
what is an amino acid structure
N terminal and C terminal - carbon is chiral except in glycine
how do amino acids behave in water
if side chain is polar - hydrophilic - on protein surface
if side chain is non polar - hydrophobic - buried in core
what are the effects of ph on amino acids
H is lost if in base
H is gained if in acid
what is enkephalin
a pentapeptide endorphin
natural brain opiod
binds to opiod recptors - affects pain reception
what are the levels of protein structure
primary - amino acid sequence
secondary - alpha helix, hydrogen bonding
tertiary - folding, 3d shape, function derived
quarternary - multiple peptides together
what are fibrous and globular proteins
fibrous - hair, primary structure repetitive
globular - intricately folded so that sidechains are sheltered eg enzymes
what happens to proteins at high temps and ph
denaturation
hydrogen bonds break - secondary and tertiary structure affected so function is affected
what is the isoelectric point
the ph that makes the overall charge of a protein zero
if ph is lower, charge is positive
if ph is higher, charge is negative
when charge is zero proteins aggregate - least soluble form
what are lipoproteins, glycoproteins, and nucleoproteins
lipoproteins - carry fat around blood
glycoproteins - proteins with oligosaccharides eg antibodies, receptors, hormones
nucleoproteins - ribosomes, virus particles