Amino Acids Example Questions Flashcards
The side chain of this amino acid usually forms a covalent bond with the N atom in the peptide backbone
This amino acid is an amide of aspartic acid
Asparagine (Asn, N)
Gln
Glutamine (Q)
This amino acid contains a sulfur atom in the side chain but “acts” like other aliphatic amino acids
Methionine (M, Met)
This amino acid is ideal for tight and limited spacing
glycine
This amino acid can be phosphorylated by kinase. name all of them.
Tyrosine (Y, Tyr)
Serine (S, Ser)
Threonine (T, Thr)
This amino acid has an ionizable side chain with a pKa close to physiological pH
Histidine (His, H)
This amino acid contains a phenyl ring but can, nevertheless, be classified as a polar amino acid
tyrosine
This amino acid is commonly used to link proteins together or to link two different regions of the same protein
This amino acid contains a negatively charged side chain at neutral pH
These non-polar amino acids are isomers of each other
Leucine (Leu, L)
Isoleucine (Ile, I)
Asn
Asparagine (N)
You suspect that a particular amino acid plays a critical role in the active site of an
enzyme. To test your hypothesis, you replace (substitute) the amino acid of interest (Leu) with another amino acid.
In order to maintain the overall structure of the protein, your substitute amino needs to have similar biochemical properties. In other words, you need to make a conservative substitution.
Which amino will you choose as the replacement for leucine?
This hydrophobic amino acid contains an indole ring fused to a methyl group
Tryptophan (W, Trp)
asparagine is to aspartic acid as glutamine is to ______________.
glutamic acid