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Biol 1024 > Amino Acids > Flashcards

Amino Acids Flashcards

1
Q

Valine

A

Val/V

Non-polar

R-group= CH - (CH3)2

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2
Q

Proline

A

Pro/P

Non-polar

Reduces structural flexibility of the polypeptide

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3
Q

Alanine

A

Ala/A

Non-polar

Hydrophobic

Tend to cluster within proteins

Stabilise protein structure through hydrophobic interactions

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4
Q

Glycine

A

Gly/G

Non-polar

Adds to flexibility of polypeptides

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5
Q

Glutamate

A

Glu/E

Negatively charged R-group

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6
Q

Aspartate

A

Asp/D

Present in active sites of enzymes like HIV protease

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7
Q

Histidine

A

His/H

Positively charged R groups

Present in many enzyme active sites

Can be both proton donor and acceptor allowing buffering capability

Contains imadozole group

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8
Q

Arginine

A

Arg/R

Positively charged R-group, therefore it can allow formation of ionic bonds with negatively charged groups

Very hydrophilic

Can participate in hydrogen bonding

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9
Q

Lysine

A

Lys/K

Positively charged R-groups

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10
Q

Glutamine

A

Gln/Q

Polar

Uncharged R-groups

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11
Q

Asparagine

A

Asn/ N

Polar

Uncharged R-group

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12
Q

Cysteine

A

Cys/C

Polar

Uncharged R-groups

Contains polar sulfhydryl group, therefore can form disulphide bridges

Present in active sites

Could take part in metal ion coordination

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13
Q

Threonine

A

Thr/T

Polar

Uncharged R-groups

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14
Q

Serine

A

Ser/S

Polar

Uncharged R-groups

Present in active sites of digesting enzymes

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15
Q

Tryptophan

A

Trp/W

Has an indole group

More strong absorbance of light at 280nm than tyrosine

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16
Q

Tyrosine

A

Tyr/Y

Has a phenol group which is a potential site for phosphorylation

Can form hydrogen bonds and has slightly polar characteristics

Strong absorbance of light at 280nm

17
Q

Phenylalanine

A

Phe/F

Relatively non-polar but has hydrophobic interactions

Has phenyl group

Allows stacking interaction which leads to strong hydrophobic interactions

18
Q

Methionine

A

Met/M

Non-polar

Useful for radioactive labelling of proteins

19
Q

Isoleucine

A

Ile/l

Non-polar

20
Q

Leucine

A

Leu/L

Non-polar R-groups

Biol 1024 (2 decks)

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