Amino Acid Synthesis and Degradation Flashcards
aa’s that produce pyruvate
threonine –> glycine –>
tryptophan –>
–> alanine, serine, cysteine –> Pyruvate!
aa’s that produce oxaloacetate (TCA intermediate)
aspartate
asparagine
aa’s that produce fumarate (TCA intermediate)
aspartate
tyrosine
phenylalanine
aa’s that produce propionyl CoA (–> methylmalonyl CoA –> succinyl CoA - TCA intermediate)
Valine
Threonine
Isoleucine
Methionine
aa’s that produce glutamate (–> a-ketoglutarate - TCA intermediate)
arginine
histidine
glutamine
proline
aa’s that produce acetyl CoA (ketogenic)
threonine
lysine
isoleucine
tryptophan
aa’s that produce HMG CoA (ketogenic)
leucine
aa’s that produce acetoacetate (ketogenic)
phenylalanine
tyrosine
ketone body rxn
Acetyl CoA + Acetoacetyl CoA –> HMG CoA –> Acetoacetate (ketone bodies)
aa’s derived from intermediates of glycolysis (converted to pyruvate; can be synthesized from glucose and reconverted back to glucose)
glycine, serine, cysteine, alanine
aa’s related through glutamate
histidine glutamine glutamate proline arginine
nonessential amino acids
AAA GGG C PST alanine asparagine aspartate glycine glutamine glutamate cysteine proline serine tyrosine (*not derived from glucose)
arginine (essential during growth)
histidine (essential during growth)
essential amino acids
PVT TIM HALL phenylalanine valine threonine tryptophan isoleucine methionine histidine* arginine* leucine lysine
both glucogenic and ketogenic
threonine
tryptophan
isoleucine
phenylalanine
in THREe ISOLated incidents, Greg and Katie TRYPped and PHEll
exclusively ketogenic
leucine
lysine
