Amino acid structures Flashcards
Describe the structure and any main features of alanine
- Ala (A)
- Methyl group attached to central carbon
- Hydrophobic- found on inside of protein structure
Describe the structure and any main features of valine
- Val (V)
- CH3CHCH3 group (C2 attached to central carbon)
- Hydrophobic- found on inside of protein structure
Describe the structure and any main features of leucine
- Leu (L)
- CH2CH(CH3)CH3 Isobutyl
- Hydrophobic- found on inside of protein structure
Describe the structure and any main features of isoleucine
- Ile (I)
- CH(CH3)CH2CH3
- Hydrophobic- found on inside of protein structure
Describe the structure and any main features of Phenylalanine
- Phe (F)
- Methylbenzene - CH2 attached to main carbon
- Hydrophobic- found on inside of protein structure
Describe the structure and any main features of Proline
- Pro (P)
- CH2CH2CH2 carbon-3 (cyclic structure) joins on to NH2 group of the standard amino acid structure
- Hydrophobic- found on inside of protein structure
Describe the structure and any main features of Methionine
- Met (M)
- CH2CH2SCH3
- Hydrophobic- found on inside of protein structure
Describe the structure and any main features of Glycine
- Gly (G)
- Hydrogen
- Hydrophobic- found on inside of protein structure
- A lot of flexibility because not such a long side chain.
Describe the structure and any main features of aspartic acids
- Asp (D)
- CH2COOH
- Charged amino acids- attract to each other to form salt bridges
- Negatively charged
Describe the structure and any main features of Glutamic Acid
- Glu (E)
- CH2CH2COOH
- Charged amino acids- attract to each other to form salt bridges
- Negatively charged
Describe the structure and any main features of Arginine
- Arg (R)
- (CH2)3NHC(=NH)NH2
- Charged amino acids- attract to each other to form salt bridges
- Positively charged
Describe the structure and any main features of Lysine
- Lys (K)
- (CH2)4NH2
- Charged amino acids- attract to each other to form salt bridges
- Positively charged
Describe the structure and any main features of Serine
- Ser (S)
- CH2OH
- Polar amino acid
Describe the structure and any main features of Threonine
- Thr (T)
- CH(OH)CH3
- Polar amino acid
Describe the structure and any main features of Thryosine
- Tyr (Y)
- CH2BenzeneOH
- Polar amino acid
- Good absorber of UV- aromatic
Describe the structure and any main features of Histadine
- His (H)
- CH2(CYCLIC C-NH=CH-NH-CH=)
- Polar amino acid
- Used for cloning or purifying proteins as a tag- strong affinity to metals.
Describe the structure and any main features of Cysteine
- Cys ( C)
- CH2SH
- Polar amino acid
- Make proteins stronger- can form covalent di-sulfide bond
Describe the structure and any main features of Tryptophan
- Trp (W)
- CH2(CYCLIC C=CH-NH-C=C-) Benzene attached to carbon=carbon in cyclic ring.
- Polar amino acid
- Aromatic- absorb UV
Describe the structure and any main features of Asparagine
- (Asn (N)
- CH2C=ONH2
- Polar amino acid
Describe the structure and any main features of Glutamine
- Gln (Q)
- CH2CH2C=ONH2
- Polar amino acid
Name the aliphatic amino acids
- Alanine A
- Valine V
- Leucine L
- Isoleucine I
Name the aromatic amino acids and state their properties
- Phenylalanine F
- Thyrosine Y
- Tryptophan W
- All absorb UV: W is best then Y then F
Name four common features of all amino acids
- Carboxyl group
- Amino group
- Side chain (R group)- distinguishing feature
- H atom