Amino Acid Metabolism

Question 1

Pepsin

Answer 1

Pepsinogen from chief cell autoactivated HCl, cleaves before large hydrophobic amino acids

Question 2

Trypsin

Answer 2

Pancreatic acinar cells secrete tyrpsinogen, activated by enteropeptidased, basic amino acid cleavage

Question 3

Elastase

Answer 3

Proelastase to elastase by trypsin from pancreas, cleave at small AA

Question 4

Chymotrypsin

Answer 4

Chymotrypsinogen to chymotrypsin by trypsin from pancreas, cleave at aromatic AA

Question 5

Cystinuria

Answer 5

Basic AA transporter deficiency

Question 6

Degradation to Acetoacetate CoA

Answer 6

Lys, Leu, Phe, Trp, Tyr

Question 7

Degradation to Acetyl CoA

Answer 7

Ile, Leu, Trp, Thr

Question 8

Degradation to KG

Answer 8

Glu, Pro, His, Arg, Gln

Question 9

Degradation to Succ CoA

Answer 9

Val, Ile, Thr, Met

Question 10

Degradation to Fum

Answer 10

Phe, Thr

Question 11

Degradation to OAA

Answer 11

Asp, Asn

Question 12

Degradation to Pyr

Answer 12

Ala, Cys, Gly, Ser, Trp, Thr

Question 13

Synthesis from Phe

Answer 13

Tyr

Question 14

Synthesis from 3PG

Answer 14

Ser to Gly, Cys

Question 15

Synthesis from Pyr

Answer 15

Ala

Question 16

Synthesis from OAA

Answer 16

Asp to Asn

Question 17

Synthesis from KG

Answer 17

Glu to Pro, Arg, Gln