amino acid Flashcards

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1
Q

what is an amino acid?

A

amino acids are organic compounds with both amino group(-NH20 and carboxyl group(cooh) attached to the same carbon. they are substituted methanes as there are four substituent groups attached to the same carbon.

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2
Q

what are the properties of amino acids?

A

amino acid never exists uncharged no matter the ph. at the isoelectric point, amino acids are zwitterions. hence in a solution of different ph , the structure of amino acid changes.

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3
Q

what are zwitterions?

A

it is a compound with a negative atom and a non-adjecent positive atom . the molecule shows both positive and negative charges.

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4
Q

what are the types of amino acids, based on the number of carboxyl and amino groups?

A

1) neutral amino acid: they contain a single nh2 and COOH group. e.g. glycine, alanine, valine

2) acidic amino acids; contain single NH2 and two COOH, group
e. g. glutamic acid , aspartic acid

3) basic amino acids: they contain two NH2 and single COOH group.
e. g. lysine, arginine

4) aromatic amino acid: the variable group in these amino acids contains aromatic rings. e.g. phenylalanine, tyrosine

5) heterocyclic amino acids: they contain heterocyclic aromatic rings.
e. g. proline, tryptophan

6) sulfur-containing amino acid: e.g.. Methionine, cysteine, homocysteine, and taurine

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5
Q

types of amino acid based on involvement in protein formation.

A

1) coded: a) involved in protein synthesis
b) there are totally 20 coding amino acids
eg: glycine, alanine, glutamic acid, methionine, aspartic acid and serine, valine

2) non-coding: non involved in protein synthesis.
eg: GABA ( neurotransmitter) : gamma amino
butyric acid
othanine citrulline(helps in urea formation)

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6
Q

types of amino acids based on production in the body/requirement in the diet.

A
1)essential amino acid: not produced in our body thus required in our diet .
   P: PHENYLALANINE
   V- VALINE
   T- TRYPTOPHAN
   T- THREONINE
    I- ISOLEUCINE
   M-METHIONINE
   H-HISTIDINE
   A-ARGININE
    L-LYSINE
   L- LEUCINE

2) non-essential protein: sufficiently produced in our body and not required in the diet.
eg: aspartic acid, glutamic acid, alanine, serine,
glycine

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7
Q

explain peptide bond.

A

when two amino acids join through an amino group of one and carboxyl group of the other by loss of water it is called a peptide bond. the structure of multiple amino acids joined by peptide bond are called oligopeptide and the product is called a polypeptide.

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8
Q

what are peptides? give examples.

A

A peptide is a short chain of amino acids. The amino acids in a peptide are connected to one another in a sequence by bonds called peptide bonds.

eg: 1)short peptides called enkephalin are formed in the CNS binds receptors of certain cells and induces analgesia(absence of pain sensation)
2) some extremely toxic mushrooms such as amanitin are peptides are well as many antibiotics.

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9
Q

function of glycine

A

glycine required in the synthesis of haem

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10
Q

function of tryptophan

A

precursors of :

1) melatonin
2) indole 3 acetic acid in plants
3) serontine (vasoconstrictor)
4) nicotinamide

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11
Q

functions of tyrosine.

A

tyrosine is converted to adrenaline and thyroxine, as well as melanin(skin pigment).

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12
Q

the function of histidine.

A

precursor of histamine

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13
Q

function of alanine

A

precursor of vitamin B5

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14
Q

what are the two semi-essential amino acids?

A

arginine and histidine.

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15
Q

some other functions of amino acids.

A

1) amino acids form organic acids which form glucose by glucogenesis
2) ornithine and citrulline are compounds of the urea cycle
3) antibiotics have non-protein amino acids
4) glutamate and cysteine are used for glutathione
5) after removal of the amino group the carbon chain of amino acid is converted to glucose

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