Amines Flashcards
Alkaloids contain which functional group
Amines
Adrenaline and ephedrine contain
secondary amino group
Novocain is used as a
it is a synthetic amino compound, used an anaearthetic in dentistry
Benadryl contains
Tertiary amino group, antihistaminic drug
Quarternary ammonium salts used as
surfactants
S1: Cyano group cannot be introduced by nucleophilic substitution of chlorine in chlorobenzene
S2: Cyanobenzene can be easily obtained from diazonium salt
Both true
S1: Cyano group can be introduced by nucleophilic substituiton in chlorobenzene
S2:Cyanobenzene can be easily obtained from diazonium salt
1 wrong
2 true
Color of para hydroxy azobenzene
Orange
Color of para amino azobenzene
yellow
mild reducing agents
hypophosphorous acid (phosphinic acid i.e. H3PO2) and ethanol;
reduce diazonium salts to benzene and themselves become phosphorous acid ( H3PO3 ) and ethanal
Yield is better in sandmeyer or gatterman
Sandmeyer ( Cu +1)
Benzene diazonium chloride
colour:
structure:
solubility:
stability:
dry state:
colourless
crystalline
soluble in water
stable in cold, reacts with water when warmed
decomposes easily in dry state
fluoroboric acid
HBF4
If temperature of diazonium salt solution is allowed to rise up to 283 Kelvin the salt becomes
Phenol
Benzene diazonium fluoroborate
solubility:
stability:
Water insoluble
Stable at room temperature
why is -NHCOCH3 (acetanilide) group less activating than amino group
Lone pair of nitrogen less available to benezene ring by resonance
These days, hindsberg is replaced by
P toluene sulphonyl chloride
addition of nitrous acid on primary amine
evolution of nitrogen and alchoohl formation, N2 used for quantitave estimation of amino acids and proteins
isocyanide / carbyl amine test is given by
aromatic and primary amines only
Aniline and arylamines are usually colourless
but get coloured on storage due to atomspheric oxidation
boiling point of isomeric amines
1>2>3
