Amides, Esters, and Anhydrides Flashcards
1
Q
What is a Lactam?
A
cyclic amides that are important in antibiotic biochemistry.
4-membered ring is a beta lactam, 5 is a gamma lactam, and 6 is a delta lactam (refers to the # of carbons in the ring)
2
Q
How does the fischer esterification work?
A
It is an acid-catalyzed reaction between a carboxylic acid and a primary alcohol, which results in an ester.
the carbonyl oxygen is protonated, then the alcohol attacks, forming a geminal diol. the OH of the carboylic acid is then protonated and leaves as water, and the oxygen of the carboxylic acid is deprotonated.
3
Q
What are lactones?
A
similar to lactams, but cyclic esters
4
Q
How are anhydrides with two different parent acids named?
A
alphabetically including the names of both acids, followed by the suffix -anhydride
