Alzheimers Disease

Question 1

Type: Familial Alzheimer’s (FAD) inheritance linked. Early or late
Non-hereditary ( AKA SPORADIC) late onset
What is the cause ?
Summary: AMYLOID PLAQUES + NEUROFIBRILLARY TANGLE =
DISRUPTION OF NORMAL BRAIN IMPULSES IN THE BRAIN.

Answer 1

1.Genetic mutation > wrongfully encodes protein AMYLOID > accumulation of AMYLOID in the brain > abnormal AMYLOID forms plaque-like material called SENILE PLAQUES.
2.Microtubules of brain neurons become tangled and distorted :
NEUROFIBRILLARY TANGLE