Alzheimers Disease

Question 1

What are the 10 warning signs of AD?

Answer 1

1. Memory loss that disrupts daily life
2. Challenges in planning or solving problems
3. Difficulty completing familiar tasks
4. Confusion with time or place
5. Trouble understanding visual images and spatial relationships
6. New problems with words in speaking or writing
7. Misplacing things and losing the ability to retrace steps
8. Decreased or poor judgment
9. Withdrawal from work or social activities
10. Changes in mood and personality

Question 2

What stage of Alzheimer’s has patients that can function independently?

Answer 2

Mild Alzheimer’s

Question 3

What stage of Alzheimer’s requires increasing care?

Answer 3

Moderate Alzheimer’s

Question 4

What stage of Alzheimer’s is considered the longest stage and requires full time care?

Answer 4

Severe Alzheimer’s

Question 5

What is the number one risk factor for Alzheimer’s?

Answer 5

Advancing age

Question 6

What are 3 other risk factors for Alzheimer’s?

Answer 6

1. Family history
2. Hereditary/ genetics
3. Education, cognitive engagement

Question 7

What race/ethnicity has 2 times greater risk of Alzheimer’s disease?

Answer 7

African Americans

Question 8

What race/ethnicity has a 1.5x greater risk for Alzheimer’s?

Answer 8

Hispanics

Question 9

True or false: women are more affected by Alzheimer’s than men

Answer 9

True

Question 10

What 2 things can increase the risk for Alzheimer’s disease?

Answer 10

1. Current smoking
2. Midlife obesity

Question 11

What are 3 things that can decrease the risk of Alzheimer’s disease?

Answer 11

1. Physical activity
2. Heart healthy diets
3. Mental and social activity

Question 12

True or false: there is a diagnostic test that can be used for Alzheimer’s

Answer 12

False

Question 13

What are the 2 cognitive syndromes recognized by DSM V?

Answer 13

1. Major neurocognitive impairment
2. Mild neurocognitive impairment

Question 14

True or false: amyloid biomarkers are used as part of routine practice

Answer 14

True

Question 15

How are the biomarkers found?

Answer 15

PET imaging or CSF

Question 16

What test is used to record cognitive changes over time?

Answer 16

Mini mental state exam

Question 17

What is the scoring for the MMSE?

Answer 17

1. 24-30: no cognitive impairment
2. 18-23: mild cognitive inmpairment
3. 0-17: severe cognitive impairment

Question 18

What test is a 3 minute screening test for cognitive impairment?

Answer 18

Mini-Cog Test

Question 19

True or false: the mini cog test is not diagnostic

Answer 19

True

Question 20

What test is used in research?

Answer 20

Alzheimer’s Disease Assessment Scale (ADAS)

Question 21

What test is longer, more comprehensive for language and literacy skills?

Answer 21

Alzheimer’s disease assessment scale

Question 22

What are 4 Nonpharmacologic therapy options?

Answer 22

1. Group support
2. Education for patient, family, caregivers
3. Physical and mental activities
4. Avoid inappropriate medications

Question 23

What are the 3 cholinesterase inhibitors?

Answer 23

1. Donepezil
2. Rivastigmine
3. Galantamine

Question 24

What are the 2 NMDA Blockers?

Answer 24

1. Memantine
2. Memantine + Donepezil ER

Question 25

Donepezil

Answer 25

Aricept

Question 26

What happens if therapy is interrupted for more than a few days?

Answer 26

Require retitration

Question 27

What 4 disease states can cholinergics effect?

Answer 27

1. COPD
2. Asthma
3. Bradycardia
4. PUD

Question 28

What happens when therapy is discontinued?

Answer 28

Patients may experience clinical deterioration

Question 29

Donepezil

Answer 29

Aricept

Question 30

What is the target dose of Donepezil?

Answer 30

10 mg/day

Question 31

Rivastigmine

Answer 31

EXELON