ALLOSTERIC REGULATION OF ENZYMES IN RESPONSE TO CELLULAR ENERGY STATUS Flashcards
Low Cellular Energy: ↑ AMP, ↓ ATP, ↓ citrate, ↓ acetyl-CoA: Regulated Enzyme?
↑ Phosphofructokinase
Low Cellular Energy: ↑ AMP, ↓ ATP, ↓ citrate, ↓ acetyl-CoA: Metabolic Response?
↑ Glycolysis
Low Cellular Energy: ↓ ATP, ↓ acetyl-CoA: Regulated Enzyme?
↑ Pyruvate kinase
Low Cellular Energy: ↑ ADP, ↑ pyruvate: Regulated Enzyme?
↑ Pyruvate dehydrogenase
Low Cellular Energy: ↓ ATP, ↓ acetyl-CoA: Metabolic Response?
↑ TCA cycle
Low Cellular Energy: ↑ ADP: Regulated Enzyme?
↑ Isocitrate dehydrogenase
Low Cellular Energy: ↑ AMP: Regulated Enzyme?
↓ Fructose-1,6-bisphosphatase
Low Cellular Energy: ↑ AMP: Metabolic Response?
↓ Gluconeogenesis
Low Cellular Energy: ↓ Malonyl-CoA: Regulated Enzyme?
↑ Carnitine acyltransferase I
Low Cellular Energy: ↓ Malonyl-CoA: Metabolic Response?
↑ Fatty acid β-oxidation
Abundant Cellular Energy: ↑ ATP, ↑ citrate: Regulated Enzyme?
↓ Phosphofructokinase
Abundant Cellular Energy: ↑ ATP, ↑ citrate: Metabolic Response?
↓ Glycolysis
Abundant Cellular Energy: ↑ ATP: Regulated Enzyme?
↓ Isocitrate dehydrogenase
Abundant Cellular Energy: ↑ ATP: Metabolic Response?
↓ TCA cycle
Abundant Cellular Energy: ↑ ATP: Regulated Enzyme?
↓ α-Ketoglutarate dehydrogenase
Abundant Cellular Energy: ↑ Acetyl-CoA: Regulated Enzymes?
↑ Pyruvate carboxylase
Abundant Cellular Energy: ↑ Acetyl-CoA: Metabolic Response?
↑ Gluconeogenesis
Abundant Cellular Energy: ↑ Citrate: Regulated Enzyme?
↑ Fructose-1,6-bisphosphatase